Case Report: Sequential leadless pacing after battery depletion in a patient with recurrent device-related infection - Report - MDSpire

Case Study: Implementation of Sequential Leadless Pacing Following Battery Exhaustion in a Patient with Persistent Device-Associated Infections

  • By

  • Assel Chinybayeva

  • Gaziza Marat

  • Zhanasyl Suleymen

  • Ayan Abdrakhmanov

  • July 21, 2026

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Clinical Report: Implementation of Sequential Leadless Pacing Following Battery Exhaustion

Overview

This case study evaluates the transition from a depleted Micra VR to a Micra AV pacemaker in a patient with a history of device-associated infections. The procedure was performed without complications during follow-up.

Background

Leadless pacemakers are recognized as an option for patients at high risk of device-related infections. The management of battery depletion in these devices poses a clinical challenge, particularly for patients with a history of recurrent infections and complications from traditional transvenous systems.

Data Highlights

ParameterInitial (2025)Follow-up (1 month)Follow-up (3-6 months)
Pacing Threshold (V)0.630.50-
R-wave Amplitude (mV)9.8--
Impedance (Ω)720670-650-
Atrioventricular Synchrony (%)-8084-85

Key Findings

  • The patient had a 26-year history of cardiac pacing with multiple complications.
  • Transition to a leadless pacemaker occurred in 2017 due to recurrent infections.
  • Sequential implantation of a Micra AV pacemaker was performed in 2025 after battery depletion of the Micra VR.
  • Stable electrical parameters were observed post-implantation with no complications during follow-up.
  • No evidence of mechanical interaction or electrical interference between the two devices was noted.

Clinical Implications

The findings provide insights into the management of patients with a history of device-related infections.

Conclusion

This case demonstrates the implementation of a sequential leadless pacing strategy.

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  5. 2026 HRS/AHA/APHRS/EHRA/IDSA/LAHRS/PACES/STS expert consensus statement update on cardiovascular implantable electronic device lead management and extraction - Heart Rhythm
  6. HTG770 Leadless cardiac pacemaker implantation for bradyarrhythmias: Overview final 25/02/2026
  7. Cross-Platform Retrieval of a Chronically Implanted Leadless Pacemaker Using a Dedicated Retrieval System | JACC: Case Reports
  8. 2026 HRS/AHA/APHRS/EHRA/IDSA/LAHRS/PACES/STS expert consensus statement update on cardiovascular implantable electronic device lead management and extraction - Heart Rhythm
  9. HTG770 Leadless cardiac pacemaker implantation for bradyarrhythmias: Overview final 25/02/2026
  10. Cross-Platform Retrieval of a Chronically Implanted Leadless Pacemaker Using a Dedicated Retrieval System | JACC: Case Reports

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