Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility - Report - MDSpire
Advertisement
Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility
Endometrial Thickness Does Not Contribute to the Risk of Hypertensive Disorders in Pregnancies Following IVF in Women with Male-Factor Infertility
Overview
This study investigates the relationship between endometrial thickness and hypertensive disorders of pregnancy (HDP) in women with male-factor infertility undergoing IVF.
Background
Hypertensive disorders of pregnancy (HDP) pose significant risks to maternal and fetal health, including complications such as preterm birth and low birth weight. Understanding risk factors for HDP is crucial, especially in populations undergoing assisted reproductive technologies like IVF. Previous studies have shown mixed results regarding the impact of endometrial thickness on pregnancy outcomes, necessitating further investigation.
Data Highlights
Endometrial Thickness Group
HDP Rate (%)
≤ 8 mm
3.97
8–14 mm
3.74
≥ 14 mm
3.03
Key Findings
The overall HDP rate was 3.67% among the studied population.
No significant difference in HDP rates was observed across different endometrial thickness groups (p=0.760).
Older maternal age (OR 1.10) and higher BMI (OR 2.40) were identified as significant risk factors for HDP.
Endometrial thickness was not associated with the risk of HDP in women with male-factor infertility undergoing their first frozen-thawed embryo transfer.
This study included 2,536 women aged 20–40 years with male-factor infertility.
Clinical Implications
Clinicians should consider maternal age and BMI as significant risk factors for HDP.
Conclusion
Endometrial thickness does not appear to contribute to the risk of hypertensive disorders in this specific patient population.
Researchers analyzed UK Biobank data to determine whether spending sedentary time in prolonged vs interrupted bouts was associated with subsequent cancer incidence and cancer mortality.
