Does physical activity really improve anxiety and depression in overweight or obese children and adolescents? A systematic review and meta-analysis - Report - MDSpire

Does physical activity really improve anxiety and depression in overweight or obese children and adolescents? A systematic review and meta-analysis

  • By

  • Jie Men

  • Yuxi Zhang

  • Simin Wu

  • Pengbo Wang

  • Zhengyang Yu

  • Guoyu Zhu

  • Jingwen Wang

  • Weiqi An

  • Zhaowei Li

  • Penghong Liu

  • January 16, 2026

  • 0 min

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Impact of Physical Activity on Anxiety and Depression in Overweight Youth

Overview

This meta-analysis evaluates the effects of physical activity (PA) on anxiety, depression, self-esteem, and self-worth in overweight and obese children and adolescents. The findings support PA as an effective non-pharmacological intervention that improves psychological outcomes and addresses metabolic risks in this vulnerable population.

Background

Overweight and obesity in children and adolescents are strongly associated with increased rates of depression and anxiety, with prevalence rates of depression rising from 6.2% globally to 26.7% in this group. These comorbidities contribute to long-term adverse health outcomes including metabolic disorders and increased mortality. Traditional pharmacological and psychological treatments face challenges such as side effects, high costs, and limited accessibility. Physical activity offers dual benefits by improving both mental health and metabolic parameters through neurobiological and psychosocial mechanisms, with minimal adverse effects and greater accessibility.

Data Highlights

OutcomeEffect of Physical ActivityNotes
DepressionSignificant reductionGreater effect in overweight/obese youth compared to general population
AnxietySignificant reductionComorbid anxiety symptoms improved
Self-esteem & Self-worthImprovement observedPredictors of depression positively influenced
Adverse EffectsNone serious reportedPA safer than pharmacological treatments

Key Findings

  • Physical activity significantly reduces depressive symptoms in overweight and obese children and adolescents.
  • PA also alleviates anxiety symptoms, which commonly co-occur with depression in this population.
  • Improvements in self-esteem and self-worth were observed, which are important predictors of depression outcomes.
  • PA interventions are free from serious adverse effects commonly seen with pharmacological treatments.
  • Age, degree of obesity, and racial factors may moderate the effectiveness of PA, highlighting the need for tailored interventions.
  • PA offers a flexible and accessible treatment option that can overcome barriers associated with traditional therapies.

Clinical Implications

Clinicians should consider incorporating physical activity as a first-line or adjunctive treatment for overweight and obese youth presenting with anxiety and depression. PA not only improves psychological symptoms but also addresses metabolic risks without the side effects associated with medications. Tailoring PA programs to individual patient characteristics such as age and obesity severity may optimize outcomes.

Conclusion

Physical activity is a safe, effective, and accessible intervention that simultaneously targets the psychological and metabolic challenges faced by overweight and obese children and adolescents. Its integration into clinical practice can improve mental health outcomes and reduce long-term health risks in this vulnerable population.

References

  1. World Health Organization 2024 -- Global prevalence of depression among youth
  2. Lan Chen et al. -- Meta-analysis on PA effects in overweight/obese youth
  3. American Psychiatric Association -- Clinical guidelines for pediatric depression and anxiety
  4. WHO and NICE Guidelines -- Recommendations on physical activity for mental health

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