Mapping the gut microbiota-diabetic peripheral neuropathy research landscape: a bibliometric analysis of emerging trends and translational frontiers - Report - MDSpire
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Mapping the gut microbiota-diabetic peripheral neuropathy research landscape: a bibliometric analysis of emerging trends and translational frontiers
Clinical Report: Analyzing the Research Landscape of Gut Microbiota and DPN
Overview
This bibliometric study reveals a significant increase in research on gut microbiota and diabetic peripheral neuropathy (DPN) since 2018, highlighting key themes and emerging trends. The findings underscore the transition from associative studies to causal mechanisms and targeted interventions.
Background
Diabetic peripheral neuropathy (DPN) is a common and debilitating complication of diabetes, affecting nearly half of all patients. Understanding the role of gut microbiota in DPN pathogenesis through the gut-brain axis could lead to novel therapeutic strategies. This bibliometric analysis aims to map the intellectual landscape of this emerging research area.
Data Highlights
Year
Number of Publications
2010-2017
~20
2018-2025
113
Key Findings
133 publications were identified, with a 35.7% average annual increase post-2018.
Core research clusters include gut microbiota, neuropathic pain, and therapeutic interventions like fecal microbiota transplantation (FMT).
Keyword analysis indicates a shift from foundational concepts to interventional strategies and causal inference methodologies.
Co-citation analysis highlights significant contributions from clinical trials and animal studies on microbial metabolites.
Future research priorities include clinical translation and personalized therapeutic strategies.
Clinical Implications
The findings suggest a growing recognition of the gut-brain axis in DPN, indicating potential for novel therapeutic approaches such as FMT. Clinicians should stay informed about emerging research to consider innovative treatment options for DPN.
Conclusion
This bibliometric analysis provides a foundational understanding of the evolving research landscape linking gut microbiota and DPN, emphasizing the need for further exploration of causal mechanisms and targeted therapies.
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