Prognostic value of androgen receptor expression in ER-positive/HER2-negative breast cancer: evidence from a contemporary Chinese cohort

Expand on the implications of AR expression in the context of neoadjuvant chemotherapy and pCR.

Incorporate specific statistics on breast cancer mortality rates to provide a clearer picture of its impact.

Parameter	Result
AR Expression	Higher AR expression associated with prolonged DFS
OS Association	No significant association observed
Multivariable Analysis	AR expression, T stage, and PR expression linked to DFS
Neoadjuvant Chemotherapy	AR expression linked to DFS in patients without pCR

Higher AR expression correlates with improved disease-free survival (DFS).
No significant association between AR expression and overall survival (OS) was found.
AR expression is an independent prognostic factor in multivariable analysis.
In patients receiving neoadjuvant chemotherapy, AR expression is associated with DFS, especially in those without pathological complete response (pCR).
Further prospective studies are needed to validate these findings.

Highlight the broader implications of AR status on treatment strategies beyond just neoadjuvant chemotherapy.

Strengthen the conclusion by emphasizing the clinical relevance of AR expression and the need for ongoing research.

Clinical Report: The Prognostic Importance of Androgen Receptor Expression in ER+ Breast Cancer