The influence of chronic exercise intervention on the executive function of children with neurodevelopmental disorders: a meta-analysis - Report - MDSpire

The influence of chronic exercise intervention on the executive function of children with neurodevelopmental disorders: a meta-analysis

  • By

  • Zhengyang Zhao

  • Zhihao Feng

  • Jiaxin Deng

  • Yongfeng Liu

  • June 29, 2026

  • 0 min

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Clinical Report: The impact of long-term exercise programs on executive functioning in children with neurodevelopmental disorders

Overview

This meta-analysis evaluates the effects of chronic exercise interventions on executive function in children with neurodevelopmental disorders, primarily ADHD and ASD. The results indicate a moderate overall improvement in executive function, particularly in inhibitory control and working memory, based on the pooled data from the included studies.

Background

Neurodevelopmental disorders (NDDs) such as ADHD and ASD significantly affect children's cognitive and social functioning. This study focuses on chronic exercise as a potential non-pharmacological intervention to support these children.

Data Highlights

OutcomeEffect Size
Inhibitory ControlModerate Improvement
Working MemorySmall but Significant Improvement
Cognitive FlexibilitySmall but Statistically Significant Benefit

Key Findings

  • Chronic exercise produced a moderate overall improvement in executive function based on the meta-analysis results.
  • The largest effect was observed for inhibitory control, followed by a smaller but significant improvement in working memory.
  • Cognitive flexibility showed a small but statistically significant benefit.
  • Effects varied based on exercise type, duration, intensity, and diagnostic subtype.
  • Closed-skill exercise produced more stable benefits for inhibitory control and working memory.
  • Longer interventions were more favorable for improving inhibitory control.

Clinical Implications

The study findings indicate that chronic exercise may improve executive function in children with ADHD and ASD. Further research is needed to explore the optimal conditions for these interventions.

Conclusion

The findings from the meta-analysis indicate that tailored chronic exercise interventions can enhance executive function in children with neurodevelopmental disorders, particularly ADHD and ASD.

Related Resources & Content

  1. Frontiers in Psychiatry, 2026 -- Effects of different physical activity modalities on executive function in children with attention deficit hyperactivity disorder: a systematic review and meta-analysis
  2. Frontiers in Psychiatry, 2026 -- The impact of physical play-based games on executive functions and social behaviors in children with autism spectrum disorder: a systematic review and meta-analysis
  3. Frontiers in Psychiatry, 2026 -- The optimal exercise for improving inhibitory control in children and adolescents with NDDs: a systematic review and network meta-analysis
  4. BMC Psychiatry (Springer), 2025 -- Efficacy of game-based interventions on cognitive performance in children and adolescents with attention-deficit/hyperactivity disorder: a systematic review and meta–analysis
  5. WHO Guidelines on Physical Activity and Sedentary Behaviour, NCBI Bookshelf, 2020
  6. Physical activity and executive functions in children and adolescents with neurodevelopmental disorders: A systematic review and meta-analysis, ScienceDirect, 2025
  7. Current guidelines on physical activity for children with disabilities
  8. Physical activity and executive functions in children and adolescents with neurodevelopmental disorders: A systematic review and meta-analysis - ScienceDirect
  9. Effects of a 12-week mini-basketball exercise intervention on executive function in children with attention-deficit/hyperactivity disorder: a randomized controlled trial

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