Case Report: Persistent fetal vasculature associated with lenticular coloboma - Report - MDSpire

Case Report: Persistent fetal vasculature associated with lenticular coloboma

  • By

  • Naiyu Sun

  • Jinchang Tian

  • Hong Zhang

  • July 10, 2026

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Clinical Report: Co-occurrence of Persistent Fetal Vasculature and Lenticular Coloboma

Background

Persistent fetal vasculature (PFV) is a rare congenital ocular anomaly resulting from the failure of normal regression of the embryonic hyaloid vasculature. It can lead to various anterior and posterior segment anomalies, including cataracts and strabismus. The co-occurrence of PFV with lenticular coloboma is infrequently reported.

Data Highlights

No numerical or trial data available in the source material.

Key Findings

  • A 23-year-old female presented with poor vision due to anterior PFV and lenticular coloboma.
  • AS-OCT provided clear visualization of the fibrous stalk and lens defects.
  • The patient underwent optimized surgical intervention, including cataract extraction and anterior vitrectomy.
  • A capsular tension ring was implanted, and an intraocular lens was placed in the capsular bag.
  • This case highlights the use of AS-OCT in diagnosing complex ocular anomalies.

Clinical Implications

The findings underscore the need for thorough examination techniques, such as AS-OCT, in diagnosing ocular anomalies like PFV and coloboma. Surgical strategies should be tailored to address the unique challenges presented by these co-occurring conditions.

Conclusion

This case illustrates the coexistence of PFV and lenticular coloboma, highlighting the role of advanced imaging techniques and surgical approaches.

Related Resources & Content

  1. Frontiers | Case Report: Persistent fetal vasculature associated with lenticular coloboma
  2. Pediatric Cardiology — Prenatal Identification of Isolated Persistent Left Superior Vena Cava with Absent Right Superior Vena Cava: A Case Series
  3. Pediatric Cardiology — The Role of Chiari's Network in Fetal and Neonatal Health Issues
  4. Frontiers in Pediatrics — Isolated prenatal foramen ovale closure or restriction presenting after birth: a distinct, under-recognized clinical condition
  5. Frontiers in Medicine — Prenatal diagnosis and perinatal outcomes of umbilical cord hemangioma: two case reports and a literature-based perspective
  6. Frontiers | Case Report: Persistent fetal vasculature associated with lenticular coloboma
  7. Management and Outcomes of Posterior Persistent Fetal Vasculature - Ophthalmology
  8. Long-term Effect of Intraocular Lens vs Contact Lens Correction After Cataract Surgery During Infancy

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