Utilizing Active Fluidics at Reduced Intraocular Pressure Alleviates Intraoperative Discomfort During Phacoemulsification: A Propensity Score-Matched Analysis - Report - MDSpire

Utilizing Active Fluidics at Reduced Intraocular Pressure Alleviates Intraoperative Discomfort During Phacoemulsification: A Propensity Score-Matched Analysis

  • By

  • Yuanjiao Qiao

  • Ye Ye

  • Fangyan Liu

  • Lishi Luo

  • Xiaosheng Huang

  • Biyun Liang

  • Wenqun Xi

  • Xinhua Liu

  • Kun Zeng

  • April 22, 2026

  • 0 min

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Clinical Report: Utilizing Active Fluidics at Reduced Intraocular Pressure

Overview

This study demonstrates that phacoemulsification using active fluidics at a reduced intraocular pressure (IOP) significantly decreases intraoperative discomfort compared to traditional gravity-based fluidics. Patients in the active fluidics group reported lower pain scores and required less supplemental anesthesia.

Background

Phacoemulsification is a common surgical procedure for cataracts, yet maintaining adequate IOP is crucial for patient comfort and corneal health. Elevated IOP during surgery can lead to increased discomfort and corneal stress, highlighting the need for improved surgical techniques. Active fluidics technology allows for lower IOP maintenance, potentially enhancing patient-centered outcomes.

Data Highlights

OutcomeActive Fluidics GroupGravity-Based Fluidics Group
Supplemental Anesthesia Requirement3.1%13.8%
Median Pain Score13
Day-1 CCT Increase28.4 μm46.8 μm

Key Findings

  • Active fluidics resulted in a significantly lower requirement for supplemental anesthesia (3.1% vs. 13.8%, p = 0.028).
  • Median pain scores during surgery were lower in the active fluidics group (1 vs. 3, p < 0.001).
  • Day-1 central corneal thickness increase was less in the active fluidics group (28.4 μm vs. 46.8 μm, p < 0.001).
  • No intraoperative complications were reported in either group.
  • Endothelial cell density loss and final visual acuity were comparable between the two groups.

Clinical Implications

The findings suggest that utilizing active fluidics at lower IOP can enhance patient comfort during phacoemulsification without compromising safety or visual outcomes. Surgeons may consider adopting this technology to improve the overall surgical experience for patients.

Conclusion

Phacoemulsification with active fluidics at reduced IOP is associated with lower intraoperative discomfort and less postoperative corneal edema, supporting its use in cataract surgery.

References

  1. Retinal Physician, 2016 -- Managing IOP Increases in Small-gauge Surgery
  2. Ophthalmology Management, 2026 -- Addressing Floppy Iris Syndrome During Cataract Surgery
  3. Glaucoma Physician, 2018 -- The Role of Imaging in Microinvasive Glaucoma Surgery
  4. ESCRS -- ESCRS Recommendations for Cataract Surgery
  5. Corneal Physician — MY CORNEAL SAVE: How I Managed a Rare Post-LASIK Occurence
  6. ESCRS - ESCRS Recommendations for Cataract Surgery
  7. Surgical outcomes of phacoemulsification with different fluidics systems (centurion with active sentry vs. centurion gravity) in cataract patients with eye axial length above 26 mm

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