Incidence of herpes zoster among individuals vaccinated against COVID-19 and/or those who have contracted the virus: a cross-sectional analysis - Report - MDSpire

Incidence of herpes zoster among individuals vaccinated against COVID-19 and/or those who have contracted the virus: a cross-sectional analysis

  • By

  • Nebiha Gozde Ispir

  • Umut Pamukcu

  • Ahmet Hursit Ispir

  • Ilkay Peker

  • Meryem Toraman

  • February 7, 2026

  • 0 min

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Incidence of herpes zoster among individuals vaccinated against COVID-19

Overview

This study investigates the incidence of herpes zoster (HZ) in individuals vaccinated against COVID-19 and those who contracted the virus. The findings suggest a complex relationship between COVID-19 vaccination, infection, and the reactivation of varicella-zoster virus.

Background

Herpes zoster is a significant public health concern, particularly as its incidence may be influenced by various factors, including viral infections and vaccinations. Understanding the relationship between COVID-19 and HZ is crucial, especially given the widespread vaccination efforts against COVID-19 and the potential for viral reactivation. This study aims to clarify the incidence of HZ in vaccinated and infected individuals, contributing to the ongoing discourse on vaccine safety and viral reactivation.

Data Highlights

No specific numerical data was provided in the article.

Key Findings

  • The study utilized a self-reported questionnaire to assess HZ incidence among vaccinated and COVID-19 infected individuals.
  • Herpes zoster reactivation may occur post-COVID-19 vaccination, although the clinical significance remains unclear.
  • Conflicting results exist in the literature regarding the risk of HZ following COVID-19 vaccination.
  • Secondary infections, including herpes simplex and HZ, have been noted in patients with COVID-19.
  • Further research is needed to establish a definitive link between COVID-19 vaccination and HZ incidence.

Clinical Implications

Healthcare professionals should remain vigilant for signs of herpes zoster in patients who have received COVID-19 vaccinations or have contracted the virus. Understanding the potential for viral reactivation can aid in patient management and inform vaccination strategies.

Conclusion

The study highlights the need for further investigation into the relationship between COVID-19 vaccination and herpes zoster incidence. Continued research is essential to clarify these associations and inform clinical practice.

References

  1. Author(s)/Org, Source, Year -- Title
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  3. Author(s)/Org, Source, Year -- Title
  4. Author(s)/Org, Source, Year -- Title
  5. Author(s)/Org, Source, Year -- Title
  6. Author(s)/Org, Source, Year -- Title
  7. Recommended Adult Immunization Schedule for ages 19 years or older; 2025 U.S.
  8. Risk of herpes zoster in adults with SARS-CoV-2 infection in Spain: A population-based, retrospective cohort study - ScienceDirect

Original Source(s)

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