Precision approach for transradial access during PCI: a state-of-the-art review - Report - MDSpire

Innovative Strategies for Transradial Access in Percutaneous Coronary Intervention: A Comprehensive Review

  • By

  • Tanawat Attachaipanich

  • Muzamil Khawaja

  • Hafeez Ul Hassan Virk

  • Dmitriy N. Feldman

  • Elmir Omerovic

  • Ian C. Gilchrist

  • Arnold H. Seto

  • Chayakrit Krittanawong

  • July 21, 2026

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Clinical Report: Innovative Strategies for Transradial Access in PCI

Overview

The transradial approach (TRA) is associated with reduced bleeding and vascular complications compared to the transfemoral approach. Technical refinements and alternative access strategies like distal radial access (dTRA) are emerging to enhance procedural success.

Background

The transition from femoral to transradial access for coronary procedures has been driven by evidence showing reduced complications and mortality rates. TRA offers benefits such as decreased bleeding and faster patient mobilization.

Data Highlights

No specific numerical data provided in the source material.

Key Findings

  • TRA reduces bleeding and vascular complications compared to transfemoral access.
  • Lower mortality rates in acute coronary syndrome patients have been associated with TRA.
  • Technical refinements like ultrasound guidance and radial cocktails improve access success and reduce radial artery spasm.
  • Alternative access strategies, including dTRA and ulnar approaches, offer benefits but come with challenges such as higher crossover rates.
  • Optimal anticoagulation strategies during TRA procedures remain uncertain.

Clinical Implications

Clinicians should consider TRA for PCI due to its safety profile. Awareness of technical refinements and alternative access methods can enhance procedural success.

Conclusion

The evolution of transradial access and its refinements represent advancements in cardiac interventions.

Related Resources & Content

  1. American College of Cardiology, ACC, 2025 -- ACC/AHA Issue New Acute Coronary Syndromes Guideline
  2. American College of Cardiology, MATRIX, 2015 -- Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of AngioX: Radial vs. Femoral
  3. Clinical Research in Cardiology — Simplified radial artery haemostasis: using non-compressive dressings—the Radial Artery Puncture Haemostasis Evaluation trial: results of the RAPHE trial
  4. Frontiers in Cardiovascular Medicine — Learning curve of distal transradial access for coronary intervention: a single-center retrospective study
  5. Frontiers in Cardiovascular Medicine — Case Report: When crossing is not enough: restoring functional access in an extreme brachial artery loop during primary PCI
  6. Clinical Research in Cardiology — A Randomized Trial Comparing Distal and Proximal Transradial Access for Coronary Angiography and Interventions
  7. Simplified radial artery haemostasis: using non-compressive dressings—the Radial Artery Puncture Haemostasis Evaluation trial: results of the RAPHE trial
  8. Learning curve of distal transradial access for coronary intervention: a single-center retrospective study
  9. ACC, AHA Issue New Acute Coronary Syndromes Guideline - American College of Cardiology
  10. Minimizing Adverse Haemorrhagic Events by Transradial Access Site and Systemic Implementation of AngioX: Radial vs. Femoral - American College of Cardiology
  11. Percutaneous Coronary Intervention and vascular access complications: A contemporary review | npj Cardiovascular Health

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