Algebraic evaluation of optimization in tumors classification with numerical assessments via a flask–react web interface - Report - MDSpire

Algebraic evaluation of optimization in tumors classification with numerical assessments via a flask–react web interface

  • By

  • Nouhaila Houssa

  • Seddik Abdelalim

  • Ilias Elmouki

  • June 26, 2026

  • 0 min

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Clinical Report: Mathematical Analysis of Optimization Techniques for Tumor Classification

Overview

This study evaluates the impact of various numerical optimization methods on logistic regression models for breast and prostate cancer classification. It highlights the trade-offs between runtime, iterations, and predictive quality.

Background

Breast and prostate cancers are significant contributors to global cancer mortality, making early detection crucial. Traditional diagnostic methods have limitations, prompting the exploration of machine learning techniques.

Data Highlights

This study includes numerical experiments comparing five optimization algorithms: gradient descent, Newton-Raphson, conjugate gradient, BFGS, and L-BFGS, focusing on their convergence behavior and classification performance.

Key Findings

  • Five optimization algorithms were analyzed for their effectiveness in training logistic regression models.
  • Ridge (L2) regularization was employed to enhance numerical stability and generalization reliability.
  • Trade-offs were identified between runtime, number of iterations, and predictive quality of the models.
  • A Flask-React web application was developed to facilitate real-time cancer detection using the optimized models.
  • Healthcare professionals can visualize probabilistic predictions and class labels through the application interface.

Clinical Implications

The findings suggest that the choice of optimization method can significantly influence the performance of logistic regression models in cancer detection. Clinicians may leverage these insights to utilize more effective digital tools for early cancer diagnosis.

Conclusion

The study underscores the importance of optimization techniques in developing reliable cancer classification tools, which can enhance early detection efforts in clinical settings.

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  1. Integration of Molecular Signatures from Tumor Deposits Using Machine Learning Enhances Prognostic Assessment in Colon Adenocarcinoma, Springer, 2025 -- Title
  2. Radiographic Classification of Bone Tumours Using Recommender Systems: A Historical Perspective, European Radiology, 2024 -- Title
  3. Text-Driven Closed Loop Framework for Segmenting and Quantifying Lung Cancer Lesions, npj Digital Medicine, 2026 -- Title
  4. Machine Learning Algorithms May Help Predict Response to Immunotherapy in Patients With Advanced Melanoma, The ASCO Post, 2020 -- Title
  5. ACR Appropriateness Criteria® Female Breast Cancer Screening: 2025 Update, ScienceDirect -- Title
  6. Updates to Early Detection of Prostate Cancer: AUA/SUO Guideline (2026) | Journal of Urology, 2026 -- Title
  7. ACR Appropriateness Criteria® Female Breast Cancer Screening: 2025 Update - ScienceDirect
  8. Updates to Early Detection of Prostate Cancer: AUA/SUO Guideline (2026) | Journal of Urology
  9. Prostate-Cancer Mortality at 11 Years of Follow-up | New England Journal of Medicine

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