The risk of neoplasms in appendiceal abscess: what emergency surgeons should know - Report - MDSpire

The risk of neoplasms in appendiceal abscess: what emergency surgeons should know

  • By

  • Giulia Montori

  • Mauro Podda

  • Alessio Giordano

  • Giuseppa Procida

  • Vittoria Butera

  • Valentina Murzi

  • Paola Fugazzola

  • Carlo Bergamini

  • Fausto Catena

  • Luca Ansaloni

  • Adolfo Pisanu

  • Ferdinando Agresta

  • May 4, 2026

  • 0 min

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Clinical Report: Understanding Neoplasm Risks in Appendiceal Abscess

Overview

{'recommendation': 'Specify if interval appendectomy is recommended for all patients over 35 or only those with abscess.'}

Background

Acute appendicitis is a common surgical emergency, and its complications can lead to significant clinical challenges. The presence of a periappendiceal abscess raises concerns about the potential for underlying neoplasms, which are rare in uncomplicated cases. Understanding the risks associated with complicated appendicitis is crucial for guiding management strategies and ensuring patient safety.

Data Highlights

{'clarification': 'Ensure incidence rates are clearly attributed to the correct patient populations.'}

Key Findings

{'addition': 'Include a finding about the rarity of malignancy in pediatric cases.'}

Clinical Implications

{'emphasis': 'Highlight the limitations of preoperative imaging in detecting neoplasms.'}

Conclusion

{'suggestion': 'Identify specific areas for future research.'}

References

  1. ASCO Post, 2022 -- Younger Patients With Appendicitis May Be at Increased Risk for Appendiceal Cancer
  2. Neoplastic Findings and Outcomes in Patients Undergoing Surgery for Suspected Acute Appendicitis, 2020
  3. Journal of Gastrointestinal Surgery, 2008 -- Appendiceal Carcinoid Tumors: A Study of 1,485 Consecutive Emergency Appendectomies
  4. Examining the Link Between Appendicitis Severity, Patient Age, and Appendiceal Neoplasm Histology, 2022
  5. Diagnosis and Treatment of Acute Appendicitis: 2025 Edition of the World Society of Emergency Surgery Jerusalem Guidelines
  6. Appendiceal Tumor Prevalence in Patients With Periappendicular Abscess, 2025
  7. Consensus Guideline for the Management of Patients with Appendiceal Tumors, Part 1, 2025
  8. Diagnosis and Treatment of Acute Appendicitis: 2025 Edition of the World Society of Emergency Surgery Jerusalem Guidelines - PubMed
  9. Appendiceal Tumor Prevalence in Patients With Periappendicular Abscess - PubMed
  10. Consensus Guideline for the Management of Patients with Appendiceal Tumors, Part 1: Appendiceal Tumors Without Peritoneal Involvement | Annals of Surgical Oncology | Springer Nature Link

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