From innovation to implementation: a case report on virtual reality for chronic pain and psychological well-being in clinical practice - Report - MDSpire
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Translating Innovation into Practice: A Case Study on the Use of Virtual Reality for Managing Chronic Pain and Enhancing Psychological Health in Clinical Settings

  • By

  • Naiomi Rivera-Rivera

  • Janet Lopez

  • Nicole Haberland

  • Brendaliz Diaz-Guevara

  • August 12, 2026

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Clinical Report: Virtual Reality for Managing Chronic Pain in Veterans

Overview

This case series evaluates the implementation of RelieVRx, a virtual reality intervention, in managing chronic pain among Veterans in the Caribbean. Results indicate that two participants reported decreases in subjective pain levels, while one reported no change. All participants noted improvements in mood.

Background

Chronic pain is a prevalent issue among Veterans, often complicating management with traditional methods. The integration of non-pharmacologic therapies, such as virtual reality (VR), is increasingly recognized as essential in comprehensive pain management strategies. Understanding the real-world application of VR interventions can enhance patient engagement and outcomes in interdisciplinary care settings.

Data Highlights

VeteranSubjective Pain ChangeMood ImprovementAnxiety/Depression Improvement
1DecreaseYesYes
2DecreaseYesYes
3No ChangeYesNo

Key Findings

  • RelieVRx was integrated into the Interdisciplinary Pain Rehabilitation Program at the VA Caribbean Healthcare System.
  • Three Veterans participated in 56 sequential sessions of RelieVRx.
  • Two Veterans reported decreases in subjective pain levels, while one reported no change.
  • All participants noted improvements in mood, with qualitative feedback indicating better emotional regulation.
  • Two Veterans exhibited improvements in depressive and anxiety symptoms.

Clinical Implications

The findings indicate that VR interventions like RelieVRx were integrated into pain management programs. Clinicians may consider incorporating such non-pharmacologic options in their treatment plans for chronic pain based on observed outcomes.

Conclusion

RelieVRx was integrated into the management of chronic pain among Veterans, warranting further exploration in broader clinical settings.

Related Resources & Content

  1. MDSpire News, Virtual Reality for Pain Management: New Results, 2023 -- Benefit of immersive virtual reality vs two other conditions for chronic pain management
  2. the medicine maker, A Pain-Free Reality, 2022 -- Can virtual reality be used to control pain?
  3. Journal of Medical Internet Research (JMIR), National Acceptance and Determinants of Immersive Extended Reality in Health Care in China: Cross-Sectional Study, 2026
  4. npj Digital Medicine, Randomized-controlled trial of skills-based vr vs. distraction vr vs. sham VR for chronic low back pain, 2026
  5. WHO guideline for non-surgical management of chronic primary low back pain, 2023
  6. DEN210014 Decision Summary, 2021 -- FDA De Novo marketing authorization for RelieVRx
  7. A synthesis of meta-analyses of immersive virtual reality interventions in pain, PubMed, 2023
  8. WHO guideline for non-surgical management of
  9. DEN210014 Decision Summary
  10. A synthesis of meta-analyses of immersive virtual reality interventions in pain - PubMed

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