Characteristics of Patients Requiring Multiple Photorefractive Keratectomy (PRK) Procedures: A Retrospective Cohort Analysis - Report - MDSpire
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Characteristics of Patients Requiring Multiple Photorefractive Keratectomy (PRK) Procedures: A Retrospective Cohort Analysis

  • By

  • Ulfat Anjum

  • Hesam Hashemian

  • Masoud Khorrami-Nejad

  • Reza Yousefi

  • October 27, 2025

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Clinical Report: Characteristics of Patients Requiring Multiple PRK Procedures

Overview

This study investigates the baseline clinical features of patients needing multiple photorefractive keratectomy (PRK) procedures. It identifies preoperative hyperopia, higher astigmatism, and greater corneal irregularity as independent predictors for repeat surgeries.

Background

Uncorrected refractive error is a leading cause of visual impairment globally, driving the demand for effective surgical solutions like PRK. Despite advancements in refractive surgery, some patients require multiple PRK procedures to achieve optimal vision. Understanding the characteristics of these patients is essential for improving surgical outcomes and patient satisfaction.

Data Highlights

No numerical data available in the provided material.

Key Findings

  • Approximately 10-20% of patients may seek enhancement procedures after primary PRK.
  • Preoperative hyperopia, higher astigmatism, and greater corneal irregularity are predictors of needing multiple PRK procedures.
  • The average retreatment rate for PRK is reported to be around 6-7% across various studies.
  • Long-term efficacy of PRK may decrease after 15 years.
  • Corneal topographic parameters correlate with PRK stability, influencing the likelihood of needing repeat procedures.

Clinical Implications

Clinicians should assess preoperative characteristics such as hyperopia and astigmatism when considering PRK for patients. Awareness of the potential need for repeat procedures can help in setting realistic expectations and improving patient counseling.

Conclusion

Identifying patients at risk for requiring multiple PRK procedures can enhance surgical planning and patient outcomes. Further research is needed to refine patient selection criteria for PRK.

Related Resources & Content

  1. Clinical features of patients who needed more than one-time photorefractive keratectomy (PRK), a retrospective cohort study | BMC Ophthalmology | Full Text, 2025
  2. The efficacy, safety and predictability in transepithelial photorefractive keratectomy versus LASIK/SMILE: A meta-analysis, 2026
  3. Contact Lens Spectrum — Laser Vision Correction: Part 2, 1996
  4. Ophthalmology Management — Why PRK Is Not Dead, 2000
  5. Contact Lens Spectrum — Recent Research in the Treatment of Anterior Segment Eye Disease, 2000
  6. Contact Lens Spectrum — Online Photo Diagnosis
  7. The efficacy, safety and predictability in transepithelial photorefractive keratectomy versus LASIK/SMILE: A meta-analysis - Alexandra Serfözö, Yaser Abu Dail, Cristian Munteanu, Zamira Hoxha, Berthold Seitz, Loay Daas, 2026
  8. Clinical features of patients who needed more than one-time photorefractive keratectomy (PRK), a retrospective cohort study | BMC Ophthalmology | Full Text
  9. JCRS Online Case Reports

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