Study of Human Papillomavirus Vaccine–Related Social Media Content Across Eight Social Media Platforms: Scoping Review of Communication Content, Information Sources, and Analytical Approaches - Report - MDSpire
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Analysis of Social Media Discourse on Human Papillomavirus Vaccination Across Eight Platforms: A Scoping Review of Communication Strategies, Information Sources, and Methodological Approaches

  • By

  • Yinghan Xu

  • Ruichen Cong

  • Mingxin Liu

  • Siyu Zhou

  • Masahiko Sakaguchi

  • Kayoko Katayama

  • Qun Jin

  • Shoji Nishimura

  • Atsushi Ogihara

  • September 15, 2026

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Clinical Report: Analysis of Social Media Discourse on HPV Vaccination

Overview

This scoping review examines communication strategies and information sources related to HPV vaccination across eight social media platforms, highlighting challenges in public awareness and vaccine acceptance.

Background

Cervical cancer is a significant global health issue, primarily caused by high-risk HPV types. Prophylactic HPV vaccines are crucial for preventing these infections and associated cancers. However, vaccination coverage remains low due to barriers such as inadequate public awareness and concerns about vaccine safety, as noted in various studies.

Data Highlights

No numerical or trial data was provided in the source material, which limits the quantitative analysis of the findings.

Key Findings

  • HPV vaccination is essential for preventing cervical and other HPV-related cancers.
  • Public awareness and acceptance of HPV vaccination are low in many regions.
  • Social media is a critical platform for disseminating information about HPV vaccination.
  • Challenges include misinformation and varying perceptions of vaccine safety.
  • The WHO emphasizes high HPV vaccination coverage as a strategy for cervical cancer elimination.

Clinical Implications

Healthcare professionals can utilize social media to improve public understanding of HPV vaccination, focusing on addressing misinformation.

Conclusion

Effective communication strategies are necessary for increasing HPV vaccination uptake.

Related Resources & Content

  1. Bruni L, Albero G, Serrano B, et al., ICO/IARC information centre on HPV and cancer, 2023 -- Human papillomavirus and related diseases in the world: summary report
  2. Centers for Disease Control and Prevention, 2024 -- HPV vaccination
  3. World Health Organization, 2024 -- Cervical cancer elimination initiative
  4. Hanley SJB, Yoshioka E, Ito Y, et al., Vaccine, 2012 -- Acceptance of and attitudes towards human papillomavirus vaccination in Japanese mothers of adolescent girls
  5. Lei J, Ploner A, Elfström KM, et al., N Engl J Med, 2020 -- HPV vaccination and the risk of invasive cervical cancer
  6. Journal of Medical Internet Research (JMIR) — Human Papillomavirus Vaccine Discourse and Sentiment on Reddit Before and After COVID-19: Mixed Methods Retrospective Cross-Sectional Study
  7. Journal of Medical Internet Research (JMIR) — Engagement Trends in Online Vaccine Content: Longitudinal YouTube Study
  8. JAMA Network Open — Large Language Model Chatbot Conversations vs Public Health Materials and Parental HPV Vaccination Intentions:
  9. MDSpire News — HPV Chatbots Did Not Outperform Public Materials
  10. Human Papillomavirus Vaccine Discourse and Sentiment on Reddit Before and After COVID-19
  11. Engagement Trends in Online Vaccine Content: Longitudinal YouTube Study
  12. Large Language Model Chatbot Conversations vs Public Health Materials and Parental HPV Vaccination Intentions
  13. HPV Chatbots Did Not Outperform Public Materials
  14. HPV Vaccine Recommendations | HPV | CDC
  15. Noninferiority of One HPV Vaccine Dose to Two Doses | New England Journal of Medicine
  16. Effect of the HPV vaccination programme on incidence of cervical cancer and grade 3 cervical intraepithelial neoplasia by socioeconomic deprivation in England: population based observational study | The BMJ

Original Source(s)

Study of Human Papillomavirus Vaccine–Related Social Media Content Across Eight Social Media Platforms: Scoping Review of Communication Content, Information Sources, and Analytical Approaches

  • by Yinghan Xu, Ruichen Cong, Mingxin Liu, Siyu Zhou, Masahiko Sakaguchi, Kayoko Katayama, Qun Jin, Shoji Nishimura, Atsushi Ogihara

  • September 15, 2026

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