Age-stratified diagnostic performance of the ovarian-adnexal reporting and data system for adnexal masses: a focus on school-age children, early, and middle adolescents - Report - MDSpire
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Age-stratified diagnostic performance of the ovarian-adnexal reporting and data system for adnexal masses: a focus on school-age children, early, and middle adolescents
Clinical Report: Evaluation of O-RADS Diagnostic Efficacy for Adnexal Masses
Overview
This study evaluates the diagnostic performance of the Ovarian-Adnexal Reporting and Data System (O-RADS) in pediatric patients with adnexal masses, highlighting significant age-related differences.
Background
Adnexal masses in pediatric populations are rare, with a low incidence of ovarian malignancy. Accurate risk stratification is crucial for effective management, particularly given the differences in tumor types and histopathology between children and adults. The O-RADS system aims to standardize the assessment of these masses.
Data Highlights
Age Group
Sensitivity
Specificity
AUC
PPV
School-age Children
100.0%
93.6%
0.968
71.4%
Early Adolescents
95.8%
88.5%
0.922
--
Middle Adolescents
88.2%
85.6%
0.869
29.4%
Key Findings
The study included 501 pediatric patients with adnexal masses.
O-RADS demonstrated 100.0% sensitivity and 93.6% specificity in school-age children.
In early adolescents, sensitivity was 95.8% and specificity was 88.5%.
Middle adolescents showed a decrease in sensitivity to 88.2% and specificity to 85.6%.
Positive predictive value (PPV) declined from 71.4% in school-age children to 29.4% in middle adolescents.
A significant difference in AUC was noted between middle adolescents and school-age children (P = 0.027).
Clinical Implications
The findings indicate that age-specific performance metrics should be considered when applying the O-RADS system in pediatric populations.
Conclusion
The O-RADS ultrasound system shows varying diagnostic performance across different pediatric age groups, with diminished efficacy noted in middle adolescents.
