Correction: Unraveling the transcriptome-based network of Tfh cells in primary Sjogren syndrome: insights from a systems biology approach - Report - MDSpire

Correction: Unraveling the transcriptome-based network of Tfh cells in primary Sjogren syndrome: insights from a systems biology approach

  • By

  • Danyang Luo

  • Lei Li

  • Yi Yang

  • Yulin Ye

  • Jiawei Hu

  • Yuan Zong

  • Jiawen Zhao

  • Yiming Gao

  • Haimin Xu

  • Ning Li

  • Yinyin Xie

  • Liting Jiang

  • July 13, 2026

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Correction: Elucidating the Tfh Cell Transcriptome Network in Primary Sjogren Syndrome

Background

Primary Sjögren syndrome (pSjD) is an autoimmune disorder that affects multiple organ systems, leading to significant morbidity. Understanding the transcriptomic networks of T follicular helper (Tfh) cells is crucial for elucidating the pathogenesis of pSjD.

Data Highlights

TableDescription
Table 1Phenotypes of pSS and non-pSS patients according to 2016 ACR/EULAR criteria.
Table 2Clinical information for 82 patients grouped by Tfh cell infiltration.

Key Findings

  • Correction of duplicate and missing data in Tables 1 and 2.
  • Phenotypic comparisons of pSS and non-pSS patients based on established diagnostic criteria.
  • Clinical information for patients used in RNA sequencing studies.
  • Revised supplementary tables to reflect correct data.

Clinical Implications

The correction of data in this study is vital for researchers and clinicians working on primary Sjögren syndrome.

Conclusion

This correction addresses the data integrity issues in clinical research related to primary Sjögren syndrome.

Related Resources & Content

  1. Luo D, Li L, Yang Y, et al., Frontiers in Immunology, 2023 -- Correction: Elucidating the Tfh Cell Transcriptome Network in Primary Sjogren Syndrome Through a Systems Biology Perspective
  2. Frontiers in Immunology — Pathogenesis of renal involvement in primary Sjögren’s disease: convergence of multifactorial mechanisms on immune dysregulation
  3. Frontiers in Immunology — Characteristics of peripheral blood neutrophil subsets in patients with primary Sjogren’s syndrome based on single-cell RNA sequencing
  4. Frontiers in Immunology — Development of an improved preclinical humanized mouse platform representing the diverse clinical phenotypes of Sjögren’s syndrome
  5. Clinical Rheumatology (Springer) — Identification of Th17-associated genes PGAP1 and TMBIM1 as promising biomarkers for diagnosis and prognosis in systemic sclerosis: Insights from bioinformatics and murine studies
  6. Pathogenesis of renal involvement in primary Sjögren’s disease
  7. Characteristics of peripheral blood neutrophil subsets in patients with primary Sjogren’s syndrome
  8. Development of an improved preclinical humanized mouse platform for Sjögren’s syndrome
  9. American College of Rheumatology Criteria
  10. Iscalimab (CFZ533) in patients with Sjögren disease: week 24 efficacy and safety results of a randomized, placebo-controlled, phase 2b dose-ranging study - ScienceDirect

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