Outcomes of modern total joint arthroplasty in patients with dementia: a systematic review of challenges and considerations for perioperative care - Report - MDSpire

Outcomes of modern total joint arthroplasty in patients with dementia: a systematic review of challenges and considerations for perioperative care

  • By

  • Halil Bulut

  • Chuck Lam

  • Riese Hussain Patel

  • Tushar Kanti Bhadra

  • Hassan Tahir

  • Burcu Bulut-Okay

  • Erhan Okay

  • Enes Kanay

  • Korhan Ozkan

  • February 24, 2026

  • 0 min

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Clinical Report: Outcomes of Total Joint Arthroplasty in Dementia Patients

Overview

This systematic review evaluated perioperative outcomes of total joint arthroplasty (TJA) in patients with dementia. Findings indicate that dementia is associated with increased perioperative complications, longer hospital stays, higher mortality, and greater likelihood of discharge to long-term care facilities compared to non-dementia patients.

Background

Dementia affects over 55 million people worldwide and is expected to rise with aging populations. Total joint arthroplasty, including total hip and knee replacements, is a common intervention for end-stage joint disease but presents unique challenges in patients with cognitive impairment. Dementia patients often have multiple comorbidities and difficulties adhering to postoperative care, increasing risks of complications and impacting recovery. Despite these challenges, dementia is underrepresented in orthopedic outcome studies, necessitating a focused review of its impact on TJA outcomes.

Data Highlights

ParameterDementia Patients (n=13,816)Non-Dementia Patients (n=869,061)
Total Knee Arthroplasty (TKA)7,291Not specified
Total Hip Arthroplasty (THA)6,525Not specified
Increased perioperative complicationsHigher incidenceLower incidence
Hospital length of stayProlongedShorter
MortalityIncreasedLower
Discharge to skilled nursing/long-term careMore frequentLess frequent

Key Findings

  • Dementia patients undergoing TJA have a higher risk of perioperative complications including delirium and infections.
  • Mortality rates post-TJA are elevated in dementia cohorts compared to non-dementia patients.
  • Hospital stays are significantly longer for dementia patients following joint arthroplasty procedures.
  • Functional recovery is often impaired due to cognitive deficits affecting rehabilitation compliance.
  • Dementia patients are more frequently discharged to skilled nursing facilities or long-term care rather than home.
  • Perioperative management strategies differ and require tailoring to address cognitive and functional challenges in dementia patients.

Clinical Implications

Clinicians should recognize dementia as a significant risk factor for adverse outcomes after total joint arthroplasty and plan perioperative care accordingly. Enhanced multidisciplinary approaches including geriatric consultation, delirium prevention, and tailored rehabilitation protocols may improve recovery. Discharge planning should anticipate the increased need for post-acute care facilities in this population.

Conclusion

Dementia substantially impacts perioperative outcomes and recovery following total joint arthroplasty, necessitating specialized management strategies. Further research is needed to optimize care pathways and improve surgical outcomes for this vulnerable group.

References

  1. Global Dementia Statistics 2023 -- Dementia Prevalence and Projections
  2. Orthopedic Outcomes in Cognitive Impairment -- Challenges in TJA
  3. Perioperative Management of Dementia Patients -- Clinical Considerations
  4. Systematic Review Protocol -- PRISMA Guidelines and PROSPERO Registration CRD420251163436

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