Clinical Features and Prognostic Indicators in Older Adults with CAD
Overview
This study investigates the clinical characteristics and prognostic factors of elderly patients with coronary artery disease (CAD).
Background
As the global population ages, the prevalence of coronary artery disease (CAD) among older adults is increasing, presenting unique clinical challenges. This study aims to provide insights into the long-term prognosis of elderly patients with CAD.
Elderly patients (≥75 years) showed lower male prevalence, lipid levels, and BMI.
10.3% of elderly patients experienced MACE within one year.
Anemia, left main lesion, multivessel disease, and low LVEF were identified as independent predictors of MACE.
The OPT-CAD score demonstrated moderate predictive capacity for ischemic events.
The predictive performance of the OPT-CAD score was comparable to the GRACE score.
Clinical Implications
Clinicians should consider specific risk factors such as anemia and multivessel disease when assessing elderly patients with CAD. The OPT-CAD score can be utilized for predicting long-term ischemic risks, aiding in the management of these patients.
Conclusion
The study identifies significant predictors of adverse outcomes in elderly patients with CAD.
Plasma proteomic models of more than 40 cell types were associated with incident Alzheimer's disease, amyotrophic lateral sclerosis, cancer, and mortality across three large cohorts.
