Clinical Report: Impact of Peer Support on Disease Progression Anxiety in Glioma Patients

Overview

This systematic review and meta-analysis protocol aims to evaluate the effectiveness of peer support in reducing fear of disease progression (FoP) among glioma patients.

Background

Glioma patients often experience significant fear of disease progression due to the high recurrence rates and associated psychological distress. Peer support has emerged as a potential intervention to address these fears.

Data Highlights

No numerical data available as this is a protocol for a systematic review and meta-analysis.

Key Findings

• Glioma patients exhibit high levels of fear of disease progression, impacting their quality of life.
• Peer support can provide emotional, social, and practical assistance to patients managing their disease.
• Current treatment options for glioma include surgery, radiotherapy, and chemotherapy, but recurrence rates remain high.
• Fear of disease progression is correlated with increased anxiety, depression, and other adverse health outcomes.
• Effective interventions are needed to address the psychological needs of glioma patients.

Clinical Implications

The findings from this systematic review may guide the development of peer support interventions tailored for glioma patients.

Conclusion

This systematic review will provide evidence on the effectiveness of peer support in managing fear of disease progression in glioma patients.

Related Resources & Content

1. Journal of Neuro-Oncology, Enhancing Support Frameworks for Patients Recently Diagnosed with Brain Cancer, 2021 -- https://link.springer.com/article/10.1007/s11060-021-03895-4
2. Journal of Neuro-Oncology, Internet-based guided self-help for glioma patients with depressive symptoms, 2017 -- https://link.springer.com/article/10.1007/s11060-017-2712-5
3. Journal of Neuro-Oncology, Systematic Review of Shared Decision-Making Approaches in Neuro-Oncology Care, 2025 -- https://link.springer.com/article/10.1007/s11060-025-05141-7
4. NCCN Guidelines® Insights: Distress Management, Version 1.2026 -- https://pubmed.ncbi.nlm.nih.gov/41956112/?fc=20250910095158&ff=20260415102150&v=2.19.0.post6+133c1fe
5. FearLess in Neuro-Oncology: Phase I trial targeting fear of cancer recurrence, 2025 -- https://academic.oup.com/nop/article/12/5/850/8112805?utm_source=openai
6. Journal of Neuro-Oncology — Comparison of Physician-led and Questionnaire-based Psychosocial Assessments in Adults with High-Grade Glioma: Results from a Cluster-Randomized Controlled Trial (GLIOPT)
7. NCCN Guidelines® Insights: Distress Management, Version 1.2026 - PubMed
8. FearLess in Neuro-Oncology: Phase I trial targeting fear of cancer recurrence in patients with primary malignant glioma and their caregivers | Neuro-Oncology Practice | Oxford Academic
9. A randomized controlled trial testing the benefits of prosocial writing in young adult survivors of adolescent and young adult cancer - PubMed