Survivor Treatment Selection Bias in Evaluations of Virtual Transition of Care - Report - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Bias in Treatment Selection Among Survivors in Assessments of Virtual Care Transition

  • By

  • Hongmei Yang

  • Christopher D Russell

  • Amy Arnder Greene

  • Angela D Humphrey

  • September 10, 2026

Share

Bias in Treatment Selection Among Survivors in Assessments of Virtual Care Transition

Overview

The study reports that patients receiving virtual transition of care (VToC) follow-up had lower 30-day readmission rates compared to those without follow-up.

Background

The transition from in-person to virtual care has been accelerated by the COVID-19 pandemic, necessitating effective follow-up strategies to reduce hospital readmissions. Understanding biases in treatment selection is crucial for assessing the effectiveness of virtual care interventions.

Data Highlights

No numerical data provided in the source material.

Key Findings

  • VToC follow-up was associated with lower 30-day readmission rates.
  • Survivor treatment selection bias may lead to misclassification of outcomes in observational studies.
  • Patients readmitted before their scheduled VToC follow-up were categorized as not receiving follow-up.
  • Conventional risk adjustment methods do not correct for bias caused by outcome-dependent exposure assignment.
  • Intent-to-treat analysis and time-varying Cox regression models are recommended to address bias.

Clinical Implications

Accurate assessment of exposure timing and outcome is essential to avoid misinterpretation of the benefits of virtual follow-up.

Conclusion

The findings highlight the need to address survivor treatment selection bias in studies evaluating virtual care interventions.

Related Resources & Content

  1. Horman SF, Kviatkovsky M, Castillo E, et al., JMIR Med Inform, 2025 -- Virtual transition of care clinics and associated readmission rates: 3-year retrospective cohort study
  2. Glesby M, Hoover D, Ann Intern Med, 1996 -- Survivor treatment selection bias in observational studies: examples from the AIDS literature
  3. Lévesque LE, Hanley JA, Kezouh A, Suissa S, BMJ, 2010 -- Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes
  4. Journal of General Internal Medicine — Optimization of Virtual and In-Person Care Coordination Between VA Primary Care and Mental Health Teams: A Qualitative Study
  5. Journal of Medical Internet Research (JMIR) — Can Digital Tools Fix Bias in Mental Health Triage?
  6. MDSpire News — Decentralized Trials Expand Access—but Risk Inequity
  7. The ASCO Post — Attrition High but Positive Trends Observed in Web-Based Intervention Addressing Caregiver Burden
  8. Optimization of Virtual and In-Person Care Coordination Between VA Primary Care and Mental Health Teams
  9. Can Digital Tools Fix Bias in Mental Health Triage?
  10. Decentralized Trials Expand Access—but Risk Inequity
  11. 5 Effects under the Hospital Readmissions Reduction Program for FY 2026
  12. Proactive Telehealth-Based Sepsis Transition and Recovery Support, Hospital Readmission, and Mortality: A Randomized Clinical Trial
  13. JMIR Medical Informatics - Virtual Transition of Care Clinics and Associated Readmission Rates: 3-Year Retrospective Cohort Study

Original Source(s)

Related Content