Febrile Seizures and School Performance - Report - MDSpire
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Impact of Febrile Seizures on Academic Achievement in Children

  • By

  • Julie Werenberg Dreier

  • Betina B. Trabjerg

  • Theresa Wimberley

  • Bjarke Feenstra

  • Jakob Christensen

  • September 14, 2026

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Impact of Febrile Seizures on Academic Achievement in Children

Overview

This nationwide cohort study investigates the association between febrile seizures and academic performance in children. The study analyzed data from 672,119 children who completed standardized assessments in reading and mathematics from 2010 to 2019.

Background

Febrile seizures affect approximately 2% to 5% of children and are the most common neurological condition in childhood. Concerns about potential long-term effects on cognitive development and academic achievement have led to extensive research. While animal studies indicate possible cognitive dysfunction following febrile seizures, clinical consensus suggests a favorable prognosis for affected children, particularly those with simple seizures.

Data Highlights

This study analyzed data from 672,119 children who completed standardized assessments in reading and mathematics from 2010 to 2019.

Key Findings

  • Febrile seizures were defined using ICD-10 codes, focusing on children aged 3 months to 5 years.
  • Studies have generally reported no significant differences in IQ or academic performance between children with febrile seizures and their unaffected peers.
  • Subsets of children with recurrent or prolonged febrile seizures may face increased risks of adverse neurologic outcomes.
  • Ethics approval was not required for this register-based study under Danish law.
  • Findings align with previous research indicating that simple febrile seizures do not adversely affect long-term cognitive outcomes.

Clinical Implications

Healthcare professionals should be aware of the findings regarding academic performance in children with febrile seizures.

Conclusion

The study contributes to the existing body of literature on the association between febrile seizures and academic achievement in children.

Related Resources & Content

  1. BMJ Paediatrics Open, 2023 -- Association of respiratory viral detection with complex febrile seizures and hospitalisation in children after the COVID-19 pandemic: a retrospective observational study
  2. Frontiers in Neurology, 2026 -- Pyridoxine-dependent and other pyridoxine-responsive epilepsies—insights into phenotype overlapping and the long-term outcome in a cohort of 21 children
  3. Frontiers in Immunology, 2026 -- Case Report: Tocilizumab in pediatric febrile infection-related epilepsy syndrome
  4. Intensive Care Medicine, 2012 -- Incidence and Outcomes of Seizures in 204 Unconscious Pediatric Patients
  5. New England Journal of Medicine, 1998 -- Long-Term Intellectual and Behavioral Outcomes of Children with Febrile Convulsions
  6. PubMed, 2023 -- School well-being in children with epilepsy and febrile seizures: A Danish nationwide cohort study.
  7. American Academy of Pediatrics Clinical Practice Guideline
  8. Long-Term Intellectual and Behavioral Outcomes of Children with Febrile Convulsions | New England Journal of Medicine
  9. School well-being in children with epilepsy and febrile seizures: A Danish nationwide cohort study.

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