Evaluating the role of youth-onset diabetes mellitus in the context of food insecurity and preventive care: a repeated cross-sectional study using propensity score weighted machine learning analysis - Report - MDSpire

Evaluating the role of youth-onset diabetes mellitus in the context of food insecurity and preventive care: a repeated cross-sectional study using propensity score weighted machine learning analysis

  • By

  • Yu-Sheng Lee

  • Raymond C Stetson

  • Heaven Hollender

  • Matthew Evan Sprong

  • Xueli Huang

  • Karan Kumar

  • Urja Nimitkumar Joshi

  • July 8, 2026

  • 0 min

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Clinical Report: Impact of Food Insecurity on Youth-Onset Diabetes Mellitus

Overview

This study examines the association between food insecurity (FI) and youth-onset diabetes mellitus (DM) among adolescents, revealing that moderate-to-severe FI is linked to higher odds of DM. The relationship varies based on access to preventive healthcare.

Background

Youth-onset diabetes mellitus is a growing public health issue, particularly among adolescents facing socioeconomic challenges. Food insecurity is a significant social determinant of health that may adversely affect metabolic outcomes, yet its specific association with youth-onset DM and the influence of preventive care remain inadequately understood.

Data Highlights

FI StatusOdds Ratio (OR)95% Confidence Interval (CI)p-value
Moderate-to-severe FI1.551.35 to 1.77<0.0001
Mild FI (with preventive care)1.191.04 to 1.370.0126
Moderate-to-severe FI (with preventive care)1.671.46 to 1.92<0.0001
Moderate-to-severe FI (without preventive care)0.110.03 to 0.350.0002

Key Findings

  • Moderate-to-severe food insecurity is associated with higher odds of youth-onset diabetes mellitus.
  • Mild food insecurity does not show a significant association with youth-onset diabetes.
  • Access to preventive care modifies the relationship between food insecurity and diabetes diagnosis.
  • Adolescents with moderate-to-severe food insecurity lacking preventive care have lower reported diabetes diagnoses.

Clinical Implications

Healthcare providers should assess food insecurity as part of routine diabetes care for adolescents. Ensuring access to preventive healthcare may enhance diabetes detection and management in youth experiencing food insecurity.

Conclusion

The findings indicate a significant relationship between food insecurity and youth-onset diabetes, influenced by access to preventive care.

Related Resources & Content

  1. American Diabetes Association, Diabetes Care, 2026 -- Standards of Care in Diabetes—2026
  2. U.S. Preventive Services Taskforce, Recommendation, 2025 -- Food Insecurity: Screening
  3. Frontiers in Endocrinology — Identification of BMI-related high-risk feature combinations for diabetes among young adults with normal baseline fasting plasma glucose using interpretable machine learning: a health check-up cohort study
  4. The Journal of Clinical Endocrinology & Metabolism — Creation and Assessment of a Personalized Diabetes Risk Prediction Model Incorporating Tailored Preventive Intervention Outcomes
  5. The Journal of Clinical Endocrinology & Metabolism — Assessment of the MODY Risk Calculator Reveals Overestimation of Maturity-Onset Diabetes Probability in Hispanic Adolescents
  6. BMC Psychiatry (Springer) — Utilizing machine learning to assess depression risk: uncovering familial, individual, and nutritional factors
  7. Food Security in the U.S. - Key Statistics & Graphics
  8. Healthcare and Nonhealthcare Costs: Youth With Diabetes and Food Insecurity
  9. 14. Children and Adolescents: Standards of Care in Diabetes—2026 | Diabetes Care | American Diabetes Association
  10. Recommendation: Food Insecurity: Screening | United States Preventive Services Taskforce
  11. 1. Improving Care and Promoting Health in Populations: Standards of Care in Diabetes—2026 | Diabetes Care | American Diabetes Association

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