Development and outcomes of surgical and urological kidney transplantation programs in Germany: a total population analysis from 2006 to 2021 - Report - MDSpire

Development and outcomes of surgical and urological kidney transplantation programs in Germany: a total population analysis from 2006 to 2021

  • By

  • Philipp Reimold

  • Cem Aksoy

  • Jonas Beckmann

  • Aristeidis Zacharis

  • Christer Groeben

  • Philipp Karschuck

  • Nicole Eisenmenger

  • Josef Geks

  • Johannes Huber

  • Luka Flegar

  • February 1, 2024

  • 0 min

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Analysis of Surgical and Urological Kidney Transplantation Programs in Germany (2006–2021)

Overview

This study analyzed 23,599 kidney transplant cases in Germany from 2006 to 2021, comparing urological and surgical transplant programs. While the total number of kidney transplants slightly decreased, urological departments showed a significant decline in transplant volume, whereas surgical departments maintained stable numbers. Complication rates and graft outcomes were comparable between the two disciplines.

Background

Kidney transplantation (KT) is the preferred treatment for end-stage renal disease, with increasing demand due to the global rise in chronic kidney disease. In Germany, KTs have historically been performed by both urologists and surgeons, but differences in performance and outcomes between these specialties have not been well studied. Organs for transplantation come from deceased or living donors, with Germany ranking low in organ donation rates internationally. Understanding the comparative performance of urological versus surgical KT programs can inform improvements in patient care.

Data Highlights

ParameterUrology DepartmentsSurgery Departments
Total KTs (2006–2021)Decreased from 592 to 395 cases (−33.3%; p=0.01)Stable from 1259 to 1306 cases (+3.7%; p=0.59)
Number of Centers (2006 vs 2021)10 to 1119 to 25
Complication Rate (2013–2019, DDKT)Mean 18.6% (SD 3.5%)Mean 19.3% (SD 1.0%)
Proportion of Centers with <25 KTs/year (2006 vs 2021)33% to 42%26% to 37%
Proportion of Centers with <5 LDKTs/year (2006 vs 2021)33% constant20% to 24%

Key Findings

  • From 2006 to 2021, total kidney transplants in Germany decreased slightly by 8%, with urological departments experiencing a significant 33.3% decline in transplant volume.
  • Surgical departments maintained a stable transplant volume with a slight increase of 3.7% over the same period.
  • The number of centers performing KTs increased modestly in both specialties, with surgery centers rising from 19 to 25 and urology centers from 10 to 11.
  • Complication rates for deceased donor kidney transplants between 2013 and 2019 were similar between urological (18.6%) and surgical (19.3%) departments, with no statistically significant difference.
  • The proportion of centers with low annual transplant volumes (<25 KTs/year) increased in both specialties, potentially impacting program experience.
  • Living donor kidney transplant volumes remained relatively stable in urology but showed a slight increase in surgical departments.

Clinical Implications

Both urological and surgical departments provide comparable safety and graft outcomes in kidney transplantation, suggesting that either specialty can effectively manage KT programs. However, the decline in transplant volume in urological centers and the increase in low-volume centers may warrant attention to maintain expertise and optimize patient outcomes. Efforts to consolidate experience or enhance collaboration between specialties could improve program performance.

Conclusion

This comprehensive analysis reveals stable overall kidney transplant activity in Germany with shifting contributions between urological and surgical programs. Comparable complication rates and graft outcomes support the continued involvement of both specialties, while trends in center volume highlight areas for strategic focus to sustain high-quality care.

References

  1. Murray & Harrison 1954 -- First Successful Kidney Transplantation
  2. Brosig & Nagel 1963 -- First Clinically Relevant KTs in Germany
  3. Eurotransplant 2021 -- Organ Donation Rankings
  4. German Organ Procurement Organization (DSO) Reports

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