Multimodal imaging features of primary breast epithelial–myoepithelial carcinoma: a case report and literature review - Report - MDSpire

Multimodal imaging features of primary breast epithelial–myoepithelial carcinoma: a case report and literature review

  • By

  • Peilin Sha

  • Yunhao Luo

  • Xiangzhu Wang

  • Yanhong An

  • Jia Jia

  • Xue Shi

  • Xin Li

  • Mengke Xu

  • Huiyu Ge

  • Zexing Yu

  • July 1, 2026

  • 0 min

Share

Clinical Report: Imaging Characteristics of Primary Breast Epithelial–Myoepithelial Carcinoma

Background

Breast EMC is a rare biphasic malignant tumor, comprising less than 0.5% of all breast tumors. Due to its low incidence, the imaging characteristics of EMC are not well-documented, which complicates diagnosis and treatment.

Data Highlights

The case study includes multimodal imaging findings from digital mammography, CT, MRI, conventional ultrasound, SWE, and CEUS, correlated with histopathological results.

Key Findings

  • EMC is characterized by both epithelial and myoepithelial components.
  • Imaging findings can overlap with those of invasive ductal carcinoma and benign adenomyoepithelioma.
  • SWE demonstrated stiffness heterogeneity in the tumor.
  • CEUS revealed intratumoral perfusion heterogeneity.
  • Only about 150 cases of breast EMC have been reported in the literature as of 2022.

Clinical Implications

Healthcare professionals should be aware of the non-specific imaging characteristics of breast EMC, which can mimic other breast lesions.

Conclusion

This case report contributes to the limited literature on breast EMC by providing a comprehensive analysis of its imaging characteristics.

Related Resources & Content

  1. Frontiers in Oncology, 2026 -- Multimodal imaging features of primary breast epithelial–myoepithelial carcinoma: a case report and literature review
  2. World Health Organization classification of tumours of the breast 6th edition 2026 - Quinn - Histopathology - Wiley Online Library
  3. Frontiers in Oncology — Navigating the Diagnostic Pitfalls of Cystic and Solid Breast Masses: A Comparative Case Report of Metaplastic Carcinoma and Benign Lesions
  4. Frontiers in Oncology — Synchronous primary breast invasive carcinoma and breast metastasis from high-grade serous ovarian carcinoma: a case report and literature review
  5. Frontiers in Oncology — Primary large cell neuroendocrine carcinoma of the breast with metastasis in the lymph nodes: a case report and literature review
  6. Frontiers in Oncology — Localized peritoneal epithelioid clear cell subtype mesothelioma: a case report and literature review
  7. World Health Organization classification of tumours of the breast 6th edition 2026 - Quinn - Histopathology - Wiley Online Library
  8. Frontiers | Multimodal imaging features of primary breast epithelial–myoepithelial carcinoma: a case report and literature review
  9. [PDF] Clinical outcomes and prognostic factors in epithelial-myoepithelial carcinoma (EMC) of the breast. | CiteDrive

Original Source(s)

Related Content