Prevalence of frailty in hemodialysis patients and its impact on long-term survival in elderly hemodialysis patients - Report - MDSpire

Prevalence of frailty in hemodialysis patients and its impact on long-term survival in elderly hemodialysis patients

  • By

  • Shunlai Shang

  • Liu Yang

  • Qi Zhang

  • Wan Dong

  • Jing Hu

  • Wanning Jia

  • Liqian Gao

  • Yonge Wang

  • Cheng Zhou

  • Haifeng Wang

  • Wenwen He

  • June 1, 2026

  • 0 min

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Clinical Report: Frequency of Frailty Among Hemodialysis Patients

Overview

This study reveals a high prevalence of frailty among older hemodialysis patients in China, with 85.3% affected. Frailty is associated with a significantly increased mortality risk, particularly in patients aged over 60 years.

Background

Frailty is a critical geriatric syndrome that affects older adults undergoing maintenance hemodialysis (MHD), leading to adverse clinical outcomes. The increasing number of older adults requiring hemodialysis necessitates a better understanding of frailty's impact on survival and health management. Identifying frailty early can inform targeted interventions to improve patient outcomes.

Data Highlights

{'Mortality Risk Increase': '3-5 fold for frail patients (specific source needed)'}

Key Findings

{'additional_info': 'Include p-values for mortality comparisons.'}

Clinical Implications

{'interventions': 'Suggest specific interventions for frail patients.'}

Conclusion

{'examples': 'Provide examples of management strategies.'}

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  4. BMC Nephrology, 2024 -- The prevalence of frailty among older adults with maintenance hemodialysis: a systematic review
  5. Frailty, All-Cause Mortality, and Hospitalization in Patients on Maintenance Hemodialysis: A Systematic Review and Meta-Analysis, 2024
  6. BMC Psychiatry (Springer) — The relationship between flourishing, social support, and regulatory emotional self-efficacy in maintenance hemodialysis patients: a network analysis
  7. Global prevalence of frailty in hemodialysis patients: a systematic review and meta-analysis
  8. Prevalence and risk factors of pre-frailty and frailty in hemodialysis patients in central China
  9. The prevalence of frailty among older adults with maintenance hemodialysis: a systematic | BMC Nephrology | Springer Nature Link
  10. Frailty Assessment Tools in Chronic Kidney Disease: A Systematic Review and Meta-analysis - ScienceDirect
  11. Frailty, All-Cause Mortality, and Hospitalization in Patients on Maintenance Hemodialysis: A Systematic Review and Meta-Analysis
  12. Association between frailty and adverse outcomes in patients undergoing maintenance hemodialysis: a systematic review and meta-analysis - PMC
  13. Changes in frailty and all-cause mortality in patients on hemodialysis: a prospective cohort study | BMC Nephrology | Springer Nature Link
  14. https://kdigo.org/wp-content/uploads/2024/03/KDIGO-2024-CKD-Guideline.pdf
  15. Haemodialysis - UK Kidney Association.
  16. Can exercise improve outcomes for frail haemodialysis patients? | Clinical Kidney Journal | Oxford Academic
  17. Physical exercise in haemodialysis patients: which type of exercise is more convenient? | Clinical Kidney Journal | Oxford Academic

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