Real-world 24-month pain outcomes of disk percutaneous ablation and extraction versus Disc-FX nucleoplasty for lumbar discogenic pain and contained lumbar disk herniation: a single-center retrospective cohort study - Report - MDSpire

Real-world 24-month pain outcomes of disk percutaneous ablation and extraction versus Disc-FX nucleoplasty for lumbar discogenic pain and contained lumbar disk herniation: a single-center retrospective cohort study

  • By

  • Xiaohui Yang

  • Jiaxiang Ni

  • June 23, 2026

  • 0 min

Share

Long-term Pain Outcomes at 24 Months for Disk Percutaneous Ablation and Extraction

Overview

This study compares the long-term outcomes of disk percutaneous ablation and extraction (DPAE) and Disc-FX nucleoplasty in patients with lumbar discogenic pain. At 24 months, DPAE showed a mean VAS reduction of 5.29 compared to 4.17 for Disc-FX (p < 0.001).

Background

Discogenic pain and contained lumbar disk herniation are significant contributors to chronic low back pain, necessitating effective treatment strategies. Minimally invasive techniques like DPAE and Disc-FX have emerged, yet their long-term efficacy remains under-evaluated. Understanding the comparative effectiveness of these interventions is crucial for optimizing patient outcomes.

Data Highlights

OutcomeDPAEDisc-FXP-value
Mean VAS Reduction5.29 ± 2.064.17 ± 2.24< 0.001
ODI ImprovementHigherLowerAll p < 0.05
PGIC Marked ImprovementHigherLowerAll p < 0.05
Composite Success Rate70.0%51.1%All p < 0.05
Reintervention Rate7.3%14.8%p = 0.047
Complication Rate6.4%9.1%No significant difference

Key Findings

  • DPAE resulted in a mean VAS reduction of 5.29 compared to 4.17 for Disc-FX (p < 0.001).
  • Improvement in ODI was significantly better in the DPAE group.
  • Higher rates of marked improvement in PGIC were observed in the DPAE group.
  • The composite success rate was 70.0% for DPAE versus 51.1% for Disc-FX (all p < 0.05).
  • The reintervention rate was significantly lower in the DPAE group (7.3% vs. 14.8%, p = 0.047).
  • No statistically significant difference in complication rates between the two groups.

Clinical Implications

The findings suggest that DPAE may provide superior long-term pain relief and functional outcomes for patients with lumbar discogenic pain compared to Disc-FX. Clinicians should consider these results when discussing treatment options with patients.

Conclusion

DPAE appears to offer a more effective long-term treatment option for lumbar discogenic pain compared to Disc-FX. Further multicenter studies are needed to validate these findings.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Frontiers in Medicine, 2026 -- Rim enhancement on MRI predicts long-term outcomes in extruded/migrated lumbar disc herniation managed with an inflammation-preserving protocol: a 6-year prospective cohort study
  3. Author(s)/Org, Source, Year -- Suboptimal Long-Term Results Following Lumbar Disc Herniation Surgery in Patients with Previous Lumbar Spine Operations
  4. NASS Diagnosis And Treatment Of Lumbar Disc Herniation With Radiculopathy Guideline Summary - Guideline Central
  5. Lumbar disc herniation: Epidemiology, clinical and radiologic diagnosis WFNS spine committee recommendations - PMC
  6. Positive Long-Term Results in Young Adults Following Surgical Intervention for Lumbar Disc Herniation
  7. NASS Diagnosis And Treatment Of Lumbar Disc Herniation With Radiculopathy Guideline Summary
  8. Safety practices for interventional pain procedures
  9. Lumbar disc herniation: Epidemiology, clinical and radiologic diagnosis WFNS spine committee recommendations - PMC
  10. Efficacy and safety of radiofrequency thermocoagulation target therapy for lumbar disc herniation: a systematic review - PMC
  11. Long-Term Clinical Efficacy of the Disc-FX Procedure in Contained Disc Herniation: A 7-Year Follow-Up from a Single-Center Cohort Study - PubMed
  12. Outcomes of Percutaneous Laser Disc Decompression for Lumbar Disc Herniation: A Systematic Review and Meta-Analysis
  13. Comparison of different treatments for lumbar disc herniation: a network meta-analysis and systematic review | BMC Surgery | Springer Nature Link
  14. Surgical vs Nonoperative Treatment for Lumbar Disk Herniation: The Spine Patient Outcomes Research Trial (SPORT): A Randomized Trial - PMC

Original Source(s)

Related Content