Autistic- and attention-deficit/hyperactivity disorder-like traits: differential associations with burnout, depression and anxiety, and empathy among Japanese junior residents - Report - MDSpire

Autistic- and attention-deficit/hyperactivity disorder-like traits: differential associations with burnout, depression and anxiety, and empathy among Japanese junior residents

  • By

  • Takafumi Watanabe

  • Toshiya Ishii

  • Tatsuo Akechi

  • July 9, 2026

  • 0 min

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Associations of Autistic and ADHD-like Traits with Burnout and Empathy

Overview

This study examines the prevalence of autistic-like traits (ALTs) and ADHD-like traits (ADHLTs) among junior medical residents in Japan and their associations with burnout, depression, anxiety, and empathy.

Background

Burnout, depression, and anxiety are prevalent among medical trainees, impacting their well-being and patient care. Neurodevelopmental traits such as ALTs and ADHLTs may increase vulnerability to these psychological issues.

Data Highlights

The prevalence of ALTs and ADHLTs was 23.6% for each trait among the studied junior residents.

Key Findings

  • ALTs were associated with lower personal accomplishment and higher levels of depression and anxiety.
  • ADHLTs correlated with greater emotional exhaustion, a dimension of burnout.
  • Psychological flexibility, particularly progress toward values, mediated the relationship between ALTs and personal accomplishment.
  • Cognitive fusion was identified as a mediator between ADHLTs and emotional exhaustion.
  • Both neurodevelopmental traits were linked to lower physician–patient empathy.

Clinical Implications

Addressing psychological flexibility and inflexibility could be beneficial in mitigating burnout and enhancing empathy.

Conclusion

The study highlights the significant associations between neurodevelopmental traits and psychological distress among junior medical residents.

Related Resources & Content

  1. BMC Psychiatry (Springer), 2025 -- Adverse childhood experiences mediate the association between ADHD symptoms and severe psychological distress in the Japanese general population: a causal mediation analysis of 29,268 participants
  2. Frontiers in Psychiatry, 2026 -- Adverse childhood experiences and academic burnout among Chinese traditional medicine students: the serial mediating role of rumination, self-control, and resilience
  3. Frontiers in Psychiatry, 2026 -- Burnout and perceived health in medical residents after the COVID-19 pandemic: a single-center cross-sectional study
  4. ACGME Common Program, 2025 -- Common Program Requirements
  5. American Medical Association, 2025 -- Latest data shows 28.6% burnout rate among resident physicians
  6. BMC Psychiatry (Springer) — The mediating role of self-compassion in the relationship between big five personality traits and depression among Chinese preclinical medical students: a multicenter cross-sectional study
  7. 医師の働き方改革|厚生労働省
  8. Comparative Efficacy of Interventions for Burnout in Physician Residents: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials | JMA Journal
  9. ACGME Common Program
  10. Latest data shows 28.6% burnout rate among resident physicians | American Medical Association
  11. Frontiers | Burnout and perceived health in medical residents after the COVID-19 pandemic: a single-center cross-sectional study
  12. Burnout, Covert Narcissism, and Personality Traits: The Need to Distinguish Empathy Domains in Medical Residents - PubMed
  13. The experiences of autistic medical students in relation to seeking and receiving online support: A phenomenological study | PLOS One
  14. Systematic review on prevalence of ADHD, possible ADHD or ADHD symptoms in medical students
  15. The mediating role of psychological flexibility in the association of autistic-like traits with burnout and depression in medical students during clinical clerkships in Japan: a university-based cross-sectional study - PMC

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