Investigating the Impact of Acupuncture on Cerebral Hemodynamics and Efficacy in Patients with Posterior Circulation Ischemic Stroke and Vertigo: A Protocol for a Multicenter, Randomized Controlled Trial - Report - MDSpire

Investigating the Impact of Acupuncture on Cerebral Hemodynamics and Efficacy in Patients with Posterior Circulation Ischemic Stroke and Vertigo: A Protocol for a Multicenter, Randomized Controlled Trial

  • By

  • Meng Gong

  • Pei Li

  • Renyan Xiao

  • Lina Pang

  • Xiangyin Ye

  • Shufang Li

  • Taijun Jiang

  • Hong Guo

  • Hongling Duan

  • Xuemei Deng

  • Song Jin

  • April 21, 2026

  • 0 min

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Clinical Report: Investigating the Impact of Acupuncture on Cerebral Hemodynamics

Overview

This multicenter, randomized controlled trial aims to evaluate the efficacy of acupuncture in patients with posterior circulation ischemic stroke (PCIS) and vertigo. The study will assess changes in cerebral hemodynamics and clinical outcomes, providing insights into acupuncture's potential therapeutic role in this patient population.

Background

Posterior circulation ischemic stroke (PCIS) with vertigo is a prevalent condition that significantly affects rehabilitation and increases the risk of recurrence and mortality. Current treatment options are limited, with medications like betahistine being the primary choice despite a lack of disease-specific pharmacotherapy. Understanding alternative therapies such as acupuncture could enhance management strategies for patients suffering from vertigo associated with PCIS.

Data Highlights

GroupInterventionDurationPrimary Outcome
Manual AcupunctureManual acupuncture5 times weekly for 3 weeksDizziness Handicap Inventory (DHI)
Sham AcupunctureSham acupuncture5 times weekly for 3 weeksDizziness Handicap Inventory (DHI)
Western MedicationBetahistine mesilate3 times daily for 3 weeksDizziness Handicap Inventory (DHI)

Key Findings

  • The trial will enroll 234 participants, randomly assigned to three groups: manual acupuncture, sham acupuncture, and western medication.
  • Primary outcome measure is the Dizziness Handicap Inventory (DHI), with secondary outcomes including the Dizziness and Anxiety Rating Scale (DARS).
  • Acupuncture is hypothesized to improve mean flow velocity and reduce resistance index in key cerebral arteries.
  • Imaging assessments will include transcranial Doppler and MRI to evaluate changes in cerebral hemodynamics.
  • The study aims to provide evidence on the safety and efficacy of acupuncture for managing vertigo in PCIS patients.

Clinical Implications

This trial may establish acupuncture as a viable treatment option for patients with PCIS and vertigo, potentially improving clinical outcomes and quality of life. If successful, it could lead to a shift in management strategies for this patient population, integrating acupuncture into standard care protocols.

Conclusion

The ongoing study seeks to clarify the role of acupuncture in treating vertigo associated with PCIS, potentially offering new therapeutic avenues for affected patients. Results may contribute significantly to the understanding of acupuncture's efficacy in neurological rehabilitation.

References

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  7. Diagnosis and treatment of vertigo and dizziness
  8. Effects of acupuncture on ischemic stroke: A systematic review with meta-analyses and trial sequential analyses - PubMed

Original Source(s)

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