Investigating the Impact of Acupuncture on Cerebral Hemodynamics and Efficacy in Patients with Posterior Circulation Ischemic Stroke and Vertigo: A Protocol for a Multicenter, Randomized Controlled Trial - Report - MDSpire
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Investigating the Impact of Acupuncture on Cerebral Hemodynamics and Efficacy in Patients with Posterior Circulation Ischemic Stroke and Vertigo: A Protocol for a Multicenter, Randomized Controlled Trial
Clinical Report: Investigating the Impact of Acupuncture on Cerebral Hemodynamics
Overview
This multicenter, randomized controlled trial aims to evaluate the efficacy of acupuncture in patients with posterior circulation ischemic stroke (PCIS) and vertigo. The study will assess changes in cerebral hemodynamics and clinical outcomes, providing insights into acupuncture's potential therapeutic role in this patient population.
Background
Posterior circulation ischemic stroke (PCIS) with vertigo is a prevalent condition that significantly affects rehabilitation and increases the risk of recurrence and mortality. Current treatment options are limited, with medications like betahistine being the primary choice despite a lack of disease-specific pharmacotherapy. Understanding alternative therapies such as acupuncture could enhance management strategies for patients suffering from vertigo associated with PCIS.
Data Highlights
Group
Intervention
Duration
Primary Outcome
Manual Acupuncture
Manual acupuncture
5 times weekly for 3 weeks
Dizziness Handicap Inventory (DHI)
Sham Acupuncture
Sham acupuncture
5 times weekly for 3 weeks
Dizziness Handicap Inventory (DHI)
Western Medication
Betahistine mesilate
3 times daily for 3 weeks
Dizziness Handicap Inventory (DHI)
Key Findings
The trial will enroll 234 participants, randomly assigned to three groups: manual acupuncture, sham acupuncture, and western medication.
Primary outcome measure is the Dizziness Handicap Inventory (DHI), with secondary outcomes including the Dizziness and Anxiety Rating Scale (DARS).
Acupuncture is hypothesized to improve mean flow velocity and reduce resistance index in key cerebral arteries.
Imaging assessments will include transcranial Doppler and MRI to evaluate changes in cerebral hemodynamics.
The study aims to provide evidence on the safety and efficacy of acupuncture for managing vertigo in PCIS patients.
Clinical Implications
This trial may establish acupuncture as a viable treatment option for patients with PCIS and vertigo, potentially improving clinical outcomes and quality of life. If successful, it could lead to a shift in management strategies for this patient population, integrating acupuncture into standard care protocols.
Conclusion
The ongoing study seeks to clarify the role of acupuncture in treating vertigo associated with PCIS, potentially offering new therapeutic avenues for affected patients. Results may contribute significantly to the understanding of acupuncture's efficacy in neurological rehabilitation.