Association between timing of surgery and postoperative outcomes in older adults with distal femur fractures: a systematic review and meta-analysis - Report - MDSpire

Association between timing of surgery and postoperative outcomes in older adults with distal femur fractures: a systematic review and meta-analysis

  • By

  • Shota Hoshika

  • Norio Yamamoto

  • Natsumi Saka

  • Takahiro Tsuge

  • Tomoo Sato

  • Yuichi Isaji

  • Shuri Nakao

  • June 18, 2026

  • 0 min

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Clinical Report: Impact of Surgical Timing on Postoperative Results in Elderly Patients

Overview

This systematic review and meta-analysis examines the relationship between surgical timing and postoperative outcomes in elderly patients with distal femur fractures. The findings indicate mixed evidence regarding early versus delayed intervention.

Background

Distal femoral fractures are a significant concern in the aging population, representing the second most common fragility fracture after hip fractures. These injuries are associated with high mortality and complication rates, comparable to those of hip fractures. Understanding the impact of surgical timing on outcomes is crucial.

Data Highlights

No specific numerical data or trial data was provided in the source material.

Key Findings

  • Distal femoral fractures account for 3–7% of all femoral fractures but are the second most frequent fragility fracture in older adults.
  • Evidence for the impact of surgical timing on distal femoral fractures is limited and inconclusive.
  • Some studies report no significant association between early surgery and outcomes.
  • No systematic review and meta-analysis has clarified the relationship between surgical timing and postoperative outcomes for distal femoral fractures.
  • The optimal timing for surgery in this population has not been established.

Clinical Implications

Clinicians should consider the variability in evidence regarding the timing of surgery for distal femur fractures in elderly patients.

Conclusion

The review indicates that further research is needed to clarify the relationship between surgical timing and postoperative outcomes for distal femur fractures in older adults.

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  4. conexiant, Conexiant, 2023 -- Why Hip Fracture Surgery Timing Matters
  5. Naoko Onizuka et al., SAGE Journals, 2025 -- Surgical Timing and Postoperative Outcomes in Distal Femur Fractures: Does Early Intervention Matter?
  6. Effect of surgical fixation timing on in-hospital mortality and morbidity of distal femur fractures - PubMed
  7. Surgical Timing and Postoperative Outcomes in Distal Femur Fractures: Does Early Intervention Matter? - Naoko Onizuka, Gabriel Alain, Samuel Farmer, Catherine C Quatman-Yates, Carmen E Quatman, 2025
  8. Effect of surgical fixation timing on in-hospital mortality and morbidity of distal femur fractures - PubMed
  9. Retrograde intramedullary nailing versus locked plate fixation for distal femur fractures: A systematic review and meta-analysis of randomised controlled trials only - ScienceDirect

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