Pancreatic cancer burden in China from 1990 to 2023: an analysis based on the global burden of disease study 2023 - Report - MDSpire

Pancreatic cancer burden in China from 1990 to 2023: an analysis based on the global burden of disease study 2023

  • By

  • Ziyue Wang

  • Shuai Wang

  • Guomu Liu

  • Hao Wu

  • Yuguo Chen

  • July 15, 2026

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Clinical Report: Assessment of the Impact of Pancreatic Cancer in China

Background

Pancreatic cancer is a leading cause of cancer-related mortality globally, and its rising incidence in China poses a substantial public health challenge. Understanding the trends and risk factors associated with pancreatic cancer is crucial.

Data Highlights

YearIncident CasesDeathsPrevalent CasesDALYs
2023118,381114,949102,8452,765,626

Key Findings

  • In 2023, China had an estimated 118,381 incident cases of pancreatic cancer.
  • The age-standardized prevalence rate (ASPR) showed a slight increase (AAPC 0.38%).
  • High fasting plasma glucose (HFPG) was identified as a significant risk factor, surpassing smoking in attributable burden.
  • Age-specific analysis indicated rising incidence rates in both the 15–49 years and ≥75 years age groups.
  • The overall burden of pancreatic cancer was higher in males compared to females.

Clinical Implications

The findings emphasize the need for targeted prevention strategies that address metabolic risk factors, particularly in an aging population. Clinicians should be aware of the rising incidence in younger age groups and consider metabolic management in their practice.

Conclusion

The increasing burden of pancreatic cancer in China highlights the importance of ongoing surveillance and research into effective prevention strategies. Addressing the dual challenges of an aging population and emerging metabolic risks is critical for future health outcomes.

Related Resources & Content

  1. Institute for Health Metrics and Evaluation, Global Burden of Disease Study, 2023 -- Assessment of the Impact of Pancreatic Cancer in China
  2. The Impact of Elevated Body Mass Index on Colorectal Cancer in China: Analysis from 1990 to 2021 and Projections for 2035
  3. Updates in Surgery — Advancements in Surgical Oncology for Pancreatic Cancer: A Fifteen-Year Experience at a Tertiary Care Center
  4. Frontiers in Endocrinology — Burden and trends of chronic kidney disease due to type 2 diabetes mellitus in China and G20 countries, 1990–2023: a comparative analysis
  5. Journal of Medical Internet Research (JMIR) — Understanding Public Perceptions of Lung Cancer in China: Infodemiology Study of Baidu Index and Weibo Posts
  6. ESMO Clinical Practice Guideline Express Update on the management of metastatic pancreatic cancer
  7. NCCN Guidelines for Patients: Pancreatic Cancer
  8. Chinese Consensus on Early Screening and Surveillance for Pancreatic Cancer in High-risk Individuals (2026 Revision, Nanjing)
  9. NALIRIFOX versus nab-paclitaxel and gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma (NAPOLI 3): a randomised, open-label, phase 3 trial - ScienceDirect
  10. Neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy in resectable and borderline resectable pancreatic cancer (PREOPANC-2): a multicentre, open-label, phase 3 randomised trial - ScienceDirect
  11. Benefit of Adjuvant Therapy After Neoadjuvant Therapy and Resection for Patients with Pancreatic Cancer: A Systematic Review and Meta-analysis - PubMed
  12. Frontiers | Pancreatic cancer burden in China from 1990 to 2023: An analysis based on the Global Burden of Disease Study 2023
  13. Global, regional, and national burden and trends of pancreatic cancer, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 - PMC
  14. Frontiers | Trend and forecast analysis of the changing disease burden of pancreatic cancer attributable to high fasting glucose in China, 1990–2021

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