Development and validation of a machine learning–based risk prediction model for non-suicidal self-injury in adolescents - Report - MDSpire

Development and validation of a machine learning–based risk prediction model for non-suicidal self-injury in adolescents

  • By

  • Yujun Zhao

  • Qian Wang

  • Wei Liu

  • May 13, 2026

  • 0 min

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Clinical Report: Machine Learning Model for Predicting Non-Suicidal Self-Injury

Overview

This study developed a machine learning model to predict non-suicidal self-injury (NSSI) in adolescents, identifying key risk factors such as suicide-related ideation and bullying. The support vector machine model outperformed others in predictive accuracy, highlighting the importance of early identification and intervention.

Background

Non-suicidal self-injury (NSSI) is a prevalent issue among adolescents, with significant implications for mental health and suicide risk. Understanding and predicting NSSI can facilitate timely interventions, potentially reducing the incidence of more severe outcomes such as suicide. This study leverages machine learning to enhance predictive capabilities beyond traditional methods.

Data Highlights

Time PointIncidence Rate of NSSI
T124%
T223%
T322%

Key Findings

  • The SVM model showed superior performance with AUC values greater than 0.75.
  • Recall and F1 scores for the SVM model were both higher than 0.7.
  • Key predictors of NSSI included suicide-related ideation, school bullying, and depressive status.
  • The incidence rates of NSSI were approximately 24%, 23%, and 22% at T1, T2, and T3, respectively.
  • SHAP analysis confirmed the importance of psychological and environmental factors in predicting NSSI risk.

Clinical Implications

The findings underscore the necessity for clinicians to assess risk factors such as bullying and depressive symptoms in adolescents. Implementing machine learning models in clinical settings may enhance the identification of at-risk youth, allowing for targeted prevention strategies.

Conclusion

The study demonstrates the effectiveness of machine learning in predicting NSSI among adolescents, emphasizing the role of psychological factors in risk assessment. Early identification can lead to improved intervention strategies.

Related Resources & Content

  1. BMC Psychiatry (Springer) — Creation and assessment of a machine learning framework for detecting individuals at elevated risk for psychotic disorders through analysis of medical records
  2. BMC Psychiatry (Springer) — Modeling Predictive Factors for Suicidal Thoughts in Individuals Experiencing Cognitive Decline
  3. BMC Psychiatry (Springer) — Development and validation of a brief entrapment scale for adolescents with depression: psychometric evaluation and suicide risk prediction
  4. BMC Psychiatry (Springer) — Prediction of suicidal ideation and depression in the general population with subthreshold insomnia using machine learning models
  5. Can machine learning predict non-suicidal self-injury? A systematic review and meta-analysis
  6. Comparative efficacy and acceptability of psychotherapeutic, pharmacological, and combination treatments for non-suicidal self-injury in children and adolescents: a systematic review and network meta-analysis | BMC Psychiatry | Full Text
  7. Can machine learning predict non-suicidal self-injury? A systematic review and meta-analysis
  8. Comparative efficacy and acceptability of psychotherapeutic, pharmacological, and combination treatments for non-suicidal self-injury in children and adolescents: a systematic review and network meta-analysis | BMC Psychiatry | Full Text

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