Clinical-epidemiological profile of right and left colorectal cancer: exploratory study at the university hospital of USP (2012-2018) - Report - MDSpire

Epidemiological and Clinical Characteristics of Right versus Left Colorectal Cancer: An Exploratory Study at USP University Hospital (2012-2018)

  • By

  • Aline Moreira Morais

  • Paulo S. M. Alcântara

  • Joyce de Cassia Rosa de Jesus

  • Afonso M. Andrade

  • Marilia Cerqueira Seelaender

  • Jose Pinhata Otoch

  • July 20, 2026

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Epidemiological and Clinical Characteristics of Right versus Left Colorectal Cancer

Overview

This study investigates the clinical and epidemiological characteristics of cachexia in colorectal cancer patients, focusing on differences between right- and left-sided tumors. Findings indicate that cachectic patients exhibit distinct inflammatory and nutritional profiles.

Background

Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality globally. Understanding the differences in clinical outcomes between right-sided and left-sided tumors is crucial.

Data Highlights

VariableCachectic Patients (n=40)Non-Cachectic Patients (n=29)
BMILowerHigher
HemoglobinLowerHigher
AlbuminLowerHigher
CRPHigherLower
CRP/Albumin RatioHigherLower

Key Findings

  • Cachectic patients had significantly lower BMI, hemoglobin, and albumin levels.
  • Higher CRP concentrations and CRP/albumin ratios were observed in cachectic patients.
  • Cachexia was more frequent among patients with right-sided tumors, though not statistically significant.
  • Patients who died during follow-up were significantly older than survivors.
  • Accessible biomarkers like CRP and albumin are relevant for patient assessment and risk stratification.

Clinical Implications

The distinct profiles of cachectic patients suggest the need for further investigation into their management.

Conclusion

Further research is needed to explore the prognostic implications of these findings.

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