Prognostic significance of atrial functional mitral regurgitation in patients with HFpEF and end-stage renal disease
By
Yuanyuan Wang
Bingya Lv
Yangyang Chen
Zhe Wang
Botao Hu
Yu Xiao
Haodong Du
Xiaoyi Zhang
Shuai Shao
Ya Suo
Qiankun Bao
May 15, 2026
Prognostic Role of Atrial Functional Mitral Regurgitation in Patients with Heart Failure with Preserved Ejection Fraction and End-Stage Renal Disease
Overview {'suggestion': 'Specify the current status of ANP as a biomarker for AFMR.'}
Background {'suggestion': 'Expand on the pathophysiological mechanisms of AFMR.'}
Data Highlights {'suggestion': 'Add confidence intervals for HR values where missing.'}
Key Findings {'suggestion': 'Explain the clinical implications of the HR values.'}
Clinical Implications {'suggestion': 'Include specific recommendations for monitoring and intervention.'}
Conclusion {'suggestion': 'Emphasize the need for proactive management of AFMR.'}
Related Resources & Content
Clinical Research in Cardiology, 2025 -- Understanding Atrial Functional Mitral Regurgitation: Characteristics, Definitions, and Areas of Uncertainty Clinical Research in Cardiology, 2026 -- Edge-to-edge transcatheter repair of the mitral valve for severe mitral regurgitation in patients exhibiting HFpEF characteristics Clinical Research in Cardiology, 2021 -- Prognostic Implications of Hepatorenal Function After Transcatheter Edge-to-Edge Mitral Valve Repair Clinical Research in Cardiology, 2015 -- Long-term renal function and perfusion alterations in patients with heart failure and reduced ejection fraction 2025 ESC/EACTS Guidelines on Valvular Heart Disease -- Essential Messages Heart failure with preserved ejection fraction in atrial functional mitral regurgitation – Insight from the REVEAL-AFMR, ScienceDirect, 2025 Hemodynamic effects of hemodialysis: the interaction between the heart and the arteries, Journal of Nephrology, Springer Nature https://www.escardio.org/static-file/Escardio/Guidelines/Products/Essential%20Messages/2025%20Gls/2025%20Essential%20Messages_VHD.pdf Heart failure with preserved ejection fraction in atrial functional mitral regurgitation – Insight from the REVEAL-AFMR - ScienceDirect Hemodynamic effects of hemodialysis: the interaction between the heart and the arteries | Journal of Nephrology | Springer Nature Link
