Optical coherence tomography imaging device comparison study in papilloedema secondary to idiopathic intracranial hypertension - Report - MDSpire
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Comparative Study of Optical Coherence Tomography Devices in Assessing Papilloedema Associated with Idiopathic Intracranial Hypertension

  • By

  • Gabriele Berman

  • Andreas Yiangou

  • Mark Thaller

  • Nick Capewell

  • Donna Holding

  • Georgios Tsermoulas

  • Alexandra J. Sinclair

  • Richard J. Blanch

  • Susan P. Mollan

  • September 22, 2026

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Clinical Report: Comparative Study of Optical Coherence Tomography Devices

Overview

This study evaluates the agreement between two OCT devices, Heidelberg Spectralis and Zeiss Cirrus 6000, in measuring parameters related to papilloedema in patients with idiopathic intracranial hypertension (IIH).

Background

Optical Coherence Tomography (OCT) is crucial in managing idiopathic intracranial hypertension (IIH) and assessing papilloedema. Accurate and comparable measurements across different OCT devices are essential for effective clinical decision-making.

Data Highlights

No specific numerical data provided in the source material.

Key Findings

  • The study involved adults with a definite IIH diagnosis and assessed OCT measurements on the same day using two different devices.
  • Parameters measured included peripapillary RNFL thickness, maximal disc height, and macular ganglion cell layer volume.
  • Variability in RNFL thickness measurements was noted between the two OCT devices, particularly in cases of increased papilloedema.
  • Standardized protocols for OCT imaging were followed to ensure consistency in data collection.

Clinical Implications

Clinicians should be aware of the potential discrepancies in OCT measurements between different devices when assessing patients with IIH.

Conclusion

The study evaluates OCT device agreement in clinical settings for conditions like IIH.

Related Resources & Content

  1. Author(s)/Org, Source, Year -- Title
  2. Kreda SH, Optometric Management, 2009 -- Diagnosis and Management of Optic Disc Elevation
  3. The Ophthalmologist, 2026 -- Decoding Idiopathic Intracranial Hypertension
  4. PubMed, 2025 -- Diagnosis, treatment and monitoring of idiopathic intracranial hypertension: Consensus recommendations of the Austrian IIH network (AN4IH)
  5. Eye — Optical coherence tomography measurement of retinal layers above the peripapillary hyperreflective ovoid mass-like structure in true papilloedema and pseudo-papilloedema
  6. Ophthalmology Management — The papilledema dilemma
  7. Optical coherence tomography imaging device comparison study in papilloedema secondary to idiopathic intracranial hypertension
  8. Infographic: landmark trials in neuro-ophthalmology—results of the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT)
  9. Diagnosis, treatment and monitoring of idiopathic intracranial hypertension: Consensus recommendations of the Austrian IIH network (AN4IH) - PubMed

Original Source(s)

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