AI for Automated Identification of Carpal Instability on Radiographs
Overview
This study developed and validated an AI system to automatically measure and detect signs of carpal instability on conventional wrist radiographs. The AI demonstrated accurate assessments of scapholunate joint distance, scapholunate and capitolunate angles, and carpal alignment, comparing favorably to clinicians across specialties.
Background
Carpal instability occurs when carpal bones lose normal alignment under physiological loads, often due to acute trauma such as ligament ruptures or fractures. Early identification is critical to prevent progression to scapholunate dissociation and advanced collapse. Conventional radiography is the first-line imaging modality but signs of instability are frequently overlooked due to measurement variability and clinician unfamiliarity. Automated AI-based assessment could improve detection and clinical decision-making.
Data Highlights
Dataset
Number of Radiographs
Number of Patients
Years
Purpose
Dataset 1
2178
1993
2018–2019
Training AI system
Dataset 2
481
217
2017–2021
Evaluation of AI measurements
Subset of Dataset 2
193
87
2017–2021
Observer study comparing AI and clinicians
Key Findings
AI system accurately measured scapholunate (SL) joint distance, SL and capitolunate (CL) angles, and carpal alignment on standard radiographs.
Thresholds for abnormal SL joint distance were set at 3.0 mm (neutral view) and 3.7 mm (ulnar-deviated view), with age-adjusted values for children.
AI performance was validated on a balanced dataset including normal and abnormal cases, demonstrating reliability across multiple radiographic views.
Observer study showed AI measurements were comparable to or exceeded accuracy of clinicians from various specialties.
Automated detection addresses human variability and unfamiliarity with carpal measurements, potentially reducing overlooked instability signs.
Clinical Implications
The AI system provides a reliable, automated tool for early detection of carpal instability on conventional radiographs, which are commonly the first imaging modality after wrist trauma. This can assist clinicians, including non-specialists, in identifying subtle signs of ligament injury and abnormal carpal alignment, facilitating timely management to prevent progression to advanced collapse.
Conclusion
Automated AI assessment of carpal instability indicators on standard wrist radiographs is feasible and accurate, offering a valuable adjunct to clinical evaluation. Integration of such tools may improve detection rates and patient outcomes in wrist trauma care.
References
Dornberger et al 2020 -- Thresholds for Scapholunate Joint Distance
Kaawach et al 2019 -- Age-Adjusted Normal Values for SL Joint Distance
Radboud University Medical Center et al -- Study on AI for Carpal Instability
by Nils Hendrix, Ward Hendrix, Bas Maresch, Job van Amersfoort, Tineke Oosterveld-Bonsma, Stephanie Kolderman, Myrthe Vestering, Stephanie Zielinski, Karlijn Rutten, Jan Dammeier, Lee-Ling Sharon Ong, Bram van Ginneken, Matthieu Rutten