Risk factors profile and outcomes of stroke in low resources settings: a prospective and multicentric study in a sub-Saharan Africa country - Report - MDSpire
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Profile of Stroke Risk Factors and Clinical Outcomes in Resource-Limited Settings: A Multicenter Prospective Study in Angola, Sub-Saharan Africa

  • By

  • Daniela Sebastião

  • Evander Lucas

  • Pedro Lamborne

  • Antonino Francisco

  • Mauer Gonçalves

  • Mário Fresta

  • Adilson J. M. de Oliveira

  • September 15, 2026

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Profile of Stroke Risk Factors and Clinical Outcomes in Resource-Limited Settings

Overview

This study characterizes stroke risk factors and clinical outcomes in Angola, highlighting a predominance of hemorrhagic strokes and significant functional dependence among patients. Key findings include high rates of hypertension and sedentary lifestyle as primary risk factors.

Background

Stroke is a leading cause of death and disability globally, particularly impacting low- and middle-income countries. In sub-Saharan Africa, strokes often occur at younger ages and are associated with poorer outcomes compared to high-income regions. Understanding the local epidemiology of stroke is crucial for developing targeted prevention and management strategies.

Data Highlights

ParameterValue
Mean Age57.1 ± 13.5 years
Patients under 6055.7%
Ischemic Stroke Cases54%
Hemorrhagic Stroke Cases46%
Hypertension Prevalence84.4%
Sedentary Lifestyle Prevalence81.8%
Functional Independence at Discharge18%
90-Day Mortality Rate13.3%

Key Findings

  • Hypertension was the leading modifiable risk factor, present in 84.4% of patients.
  • Patients presented with strokes at a younger mean age of 57.1 years.
  • Functional independence at discharge was achieved by only 18% of patients.
  • Mortality by 90 days was 13.3%, with 4.8% occurring during hospitalization.
  • Hemorrhagic strokes accounted for 46% of cases in this cohort.

Clinical Implications

The high prevalence of hypertension and sedentary lifestyle among stroke patients in Angola indicates a need for enhanced screening and management strategies.

Conclusion

The study highlights the burden of stroke in Angola.

Related Resources & Content

  1. Frontiers in Neurology, 2026 -- Latent profile analysis of emergency department presentation characteristics in patients with acute ischemic stroke
  2. Frontiers in Cardiovascular Medicine, 2026 -- Clinical characteristics and risk factors of atrial fibrillation detection after acute ischemic stroke
  3. European Radiology, 2024 -- Influence of Ischemic Stroke Location on Early Outcomes in Basilar Artery Occlusion: A Retrospective Analysis
  4. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association | Stroke
  5. Stroke, WHO Fact Sheet, 2025
  6. Frontiers in Neurology — Risk factors for early neurological deterioration in patients with acute ischaemic stroke and assessment of short-term prognosis
  7. 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association | Stroke
  8. Stroke
  9. Mediation Analysis to Identify Individual Component Effects of the Care Bundle to Improve Functional Outcome After ICH in the INTERACT3 Study.

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