Quality of Life and Contributing Factors in Adult Tuberculosis Patients in Kembata Zone, Southern Ethiopia: A Cross-Sectional Mixed-Methods Analysis - Report - MDSpire

Quality of Life and Contributing Factors in Adult Tuberculosis Patients in Kembata Zone, Southern Ethiopia: A Cross-Sectional Mixed-Methods Analysis

  • By

  • Thomas Petros Himbego

  • Haile Workye Agezhu

  • Derebe Yohannes Sosengo

  • Mehari Belayneh Petros

  • Ayano Elias Gabriel

  • Abnet Beyene Kobro

  • Sisay Tagese Tafese

  • Endalew Dessie Birara

  • Tamirat Godebo Woyimo

  • January 19, 2026

  • 0 min

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Quality of Life and Contributing Factors in Adult Tuberculosis Patients

Overview

This study assesses the quality of life (HRQoL) of adult tuberculosis patients in Kembata Zone, Ethiopia, highlighting significant impairments across physical, psychological, and social domains. It identifies key factors influencing HRQoL, including disease severity, treatment history, and socio-demographic variables.

Background

Tuberculosis (TB) remains a major public health challenge, particularly in low-income regions where it significantly affects patients' quality of life. The impact of TB extends beyond physical health, influencing mental and social well-being, which is crucial for comprehensive patient care. Understanding the determinants of HRQoL in TB patients is essential for developing effective interventions and improving patient outcomes.

Data Highlights

No numerical data available in the provided material.

Key Findings

  • TB significantly compromises health-related quality of life (HRQoL) across multiple domains.
  • Patients with multi-drug resistant TB (MDR-TB) report worse HRQoL compared to those with drug-susceptible TB.
  • Extrapulmonary TB (EPTB) patients experience ongoing physical and psychological impairments post-treatment.
  • Socio-demographic factors, including income and social support, are critical determinants of HRQoL in TB patients.
  • There is a lack of TB-specific HRQoL instruments, particularly in African contexts.

Clinical Implications

Healthcare providers should consider the multifaceted impacts of TB on patients' quality of life when designing treatment plans. Addressing socio-demographic factors and providing psychosocial support can enhance patient outcomes and adherence to treatment.

Conclusion

The study underscores the need for integrated, patient-centered approaches in TB care that address both clinical and psychosocial aspects of health. Improving HRQoL should be a priority in TB management strategies.

References

  1. Author(s)/Org, Source, Year -- Title
  2. Open Forum Infectious Diseases, 2021 -- Infectiousness of Pulmonary Tuberculosis Cases Identified via Active and Passive Case-Finding in High-Prevalence Areas
  3. Open Forum Infectious Diseases, 2021 -- Investigating the Influence of Community Networks on M. tuberculosis Spread and Endurance in Urban African Settings with High Tuberculosis Rates
  4. Infection, 2020 -- Alterations in T-lymphocyte Populations and Associated Risk Factors in HIV-Negative Individuals with Active Tuberculosis
  5. WHO, 2025 -- Consolidated guidelines on tuberculosis, Module 4: Treatment and care
  6. TB PRACTECAL | MSF UK, 2024 -- TB PRACTECAL
  7. Post-pulmonary tuberculosis lung function: a systematic review and meta-analysis - PMC
  8. WHO consolidated guidelines on tuberculosis Modu
  9. TB PRACTECAL | MSF UK
  10. Post-pulmonary tuberculosis lung function: a systematic review and meta-analysis - PMC

Original Source(s)

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