Affiliate stigma and health-related quality of life among caregivers of people with severe mental illness in a collectivist context: a cross-sectional study - Report - MDSpire

Affiliate stigma and health-related quality of life among caregivers of people with severe mental illness in a collectivist context: a cross-sectional study

  • By

  • Peng Fu

  • Ziyi Xiong

  • Yang Liu

  • Yong Li

  • Lian Yang

  • June 12, 2026

  • 0 min

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Clinical Report: Impact of Affiliate Stigma on Caregivers' Quality of Life

Overview

This study highlights a significant negative correlation between affiliate stigma and health-related quality of life (HRQoL) among primary caregivers of individuals with severe mental disorders in Sichuan, China. The findings underscore the urgent need for interventions aimed at reducing stigma to enhance caregivers' well-being.

Background

Caregivers of individuals with severe mental disorders often experience affiliate stigma, which can adversely affect their health-related quality of life. In collectivist societies like China, where familial roles are emphasized, the psychological burdens on caregivers can be profound. Understanding the interplay between stigma and HRQoL is crucial for developing effective support strategies for this population.

Data Highlights

MeasureMean ScoreStandard Deviation
Affiliate Stigma Score48.6715.63
EQ-5D Utility Index0.950.07
EQ-VAS Self-Rated Health Score70.4817.22

Key Findings

  • The mean affiliate stigma score among caregivers was 48.67 ± 15.63.
  • The mean EQ-5D utility index score was 0.95 ± 0.07.
  • Affiliate stigma was a significant negative predictor of HRQoL (EQ-5D-3L: β = -0.0032, p < 0.001).
  • Female caregivers reported significantly lower utility index scores.
  • Lower income was significantly associated with lower self-rated health scores (EQ-VAS: β = 7.6221, p < 0.001).

Clinical Implications

Healthcare providers should be aware of the impact of affiliate stigma on caregivers' health-related quality of life. Interventions aimed at reducing stigma and providing psychological support can improve caregivers' overall well-being and caregiving capacity.

Conclusion

The findings of this study reveal a critical link between affiliate stigma and the health-related quality of life of caregivers. Addressing this stigma is essential for enhancing the support and resources available to caregivers of individuals with severe mental disorders.

Related Resources & Content

  1. Frontiers | Affiliate stigma and health-related quality of life among caregivers of people with severe mental illness in a collectivist context: a cross-sectional study
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  3. The ASCO Post — Attrition High but Positive Trends Observed in Web-Based Intervention Addressing Caregiver Burden
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  6. DIGITAL HEALTH — Exploring caregiver experiences with the altitudes digital mental health program: A thematic analysis
  7. July 2025 exceptional surveillance of psychosis and schizophrenia in adults: prevention and management (NICE guideline CG178)
  8. Frontiers | Affiliate stigma and health-related quality of life among caregivers of people with severe mental illness in a collectivist context: a cross-sectional study
  9. Systematic review and meta-analysis of family-based interventions for early psychosis: Carer and patient outcomes - ScienceDirect

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