Is dry skin a clue to diabetic retinopathy? Clinical insights from the overall dry skin score - Report - MDSpire

Is dry skin a clue to diabetic retinopathy? Clinical insights from the overall dry skin score

  • By

  • Özge Özer

  • Dilek Menteşoğlu

  • Göknur Yorulmaz

  • June 17, 2026

  • 0 min

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Clinical Report: Does Dry Skin Indicate Diabetic Retinopathy?

Overview

This study investigates the correlation between diabetic complications and skin dryness in patients with type 2 diabetes, utilizing the Overall Dry Skin (ODS) score. Findings indicate that higher ODS scores are associated with diabetic retinopathy and other complications, suggesting the ODS score may be a useful clinical tool.

Background

Diabetes mellitus is a prevalent chronic condition that can lead to various complications, including microvascular issues such as retinopathy. Skin health is often neglected in diabetes management, despite its importance in overall patient well-being. Understanding the relationship between skin dryness and diabetic complications could enhance patient care and risk assessment.

Data Highlights

ComplicationForearm ODS Score (p-value)Lower Leg ODS Score (p-value)Total ODS Score (p-value)
Retinopathy0.0030.0070.002
Nephropathy--0.047
Peripheral Polyneuropathy0.017-0.027

Key Findings

  • The total ODS score was significantly higher in patients with diabetic retinopathy (p = 0.002).
  • Forearm ODS scores were elevated in patients with peripheral polyneuropathy (p = 0.017).
  • Age (p = 0.002) and retinopathy (p = 0.042) were independently associated with total ODS scores in multivariable analysis.
  • Higher ODS scores indicate a potential risk for diabetic complications, including retinopathy.
  • Skin dryness can serve as a non-invasive indicator for assessing diabetic complications.

Clinical Implications

The Overall Dry Skin score may be integrated into routine assessments for patients with diabetes to identify those at higher risk for diabetic retinopathy. Clinicians should consider skin health as a component of diabetes management to improve patient outcomes.

Conclusion

The study highlights the potential of the ODS score as a simple tool for identifying patients at risk for diabetic retinopathy, warranting further research in larger, multicenter studies.

Related Resources & Content

  1. Contact Lens Spectrum, 2012 -- Dry Eye Dx and Tx
  2. Contact Lens Spectrum, 2020 -- DRY EYE DX AND TX
  3. Optometric Management, 2023 -- Detect Outer Retina Impairment in Diabetes
  4. Retinopathy, Neuropathy, and Foot Care: Standards of Care in Diabetes—2026
  5. optometric management — Dry Eye: Addressing Diabetic Keratopathy
  6. 12. Retinopathy, Neuropathy, and Foot Care: Standards of Care in Diabetes—2026
  7. The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus | New England Journal of Medicine

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