Influence of Environmental and Community Factors on Psoriasis: A Comprehensive Review of Pollution, Urban Design, and Socioeconomic Risk Factors - Report - MDSpire

Influence of Environmental and Community Factors on Psoriasis: A Comprehensive Review of Pollution, Urban Design, and Socioeconomic Risk Factors

  • By

  • Parsa Mokhtar

  • Josep Riera Monroig

  • Allison Kranyak

  • Wilson Liao

  • April 2, 2026

  • 0 min

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Clinical Report: Influence of Environmental and Community Factors on Psoriasis

Overview

This systematic review identifies significant associations between environmental pollutants and the incidence and severity of psoriasis. It highlights the role of socioeconomic factors and climate-related events in exacerbating the disease, emphasizing the need for further research and public health initiatives.

Background

Psoriasis affects 2-3% of the population in Western countries and is influenced by genetic and immunologic factors. However, environmental and social determinants are increasingly recognized as contributing factors to the disease's onset and severity. Understanding these influences is crucial for developing comprehensive treatment and prevention strategies.

Data Highlights

This review analyzed 26 full-text research articles, revealing consistent associations between air and chemical pollutants and psoriasis risk.

Key Findings

  • Air pollutants such as particulate matter and nitrogen oxides are linked to increased psoriasis risk.
  • Chemical pollutants like PFAS and PFOS are associated with greater disease severity.
  • Low income and education levels correlate with higher incidence and severity of psoriasis.
  • Climate-related events, including wildfires, lead to increased healthcare utilization for psoriasis.
  • Standardized exposure metrics are necessary for better understanding and comparison of results.

Clinical Implications

Healthcare professionals should consider environmental and socioeconomic factors when assessing psoriasis patients. Public health initiatives aimed at reducing harmful exposures may help mitigate disease severity and improve patient outcomes.

Conclusion

The findings underscore the importance of integrating environmental and social determinants into the understanding and management of psoriasis. Further research is essential to clarify these relationships and inform public health strategies.

References

  1. European Journal of Preventive Cardiology, 2023 -- The Cardiovascular Syndemic: Interactions of Environmental Pollution, Mental Health, and Socioeconomic Factors
  2. American Journal of Epidemiology, 2023 -- The potential effects of hypothetical PM2.5 interventions on childhood autism in different neighborhood socioeconomic contexts
  3. Clinical Rheumatology, 2022 -- Identifying Risk Factors Associated with Primary Sjögren’s Syndrome: A Comprehensive Review and Meta-Analysis
  4. European Journal of Preventive Cardiology, 2023 -- Influence of Community and Environmental Factors on the Development of New Cardiovascular Disease: A Systematic Review and Meta-Analysis
  5. Living EuroGuiDerm Guideline for the systemic treatment of psoriasis vulgaris | EDFG, 2025
  6. Mediterranean Diet and Patients With Psoriasis: The MEDIPSO Randomized Clinical Trial - PubMed
  7. Living EuroGuiDerm Guideline for the systemic treatment of psoriasis vulgaris | EDFG
  8. REVIEW https://doi.org/10.4209/aaqr.240062

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