Effects of Tai Chi combined with dietary intervention on health-promoting lifestyle and metabolic and reproductive outcomes in female college students with polycystic ovary syndrome: a randomized controlled trial - Report - MDSpire

Effects of Tai Chi combined with dietary intervention on health-promoting lifestyle and metabolic and reproductive outcomes in female college students with polycystic ovary syndrome: a randomized controlled trial

  • By

  • Jinfeng Ren

  • Huanhuan Chen

  • Lei Zhang

  • Chenchen Cui

  • Lu Wang

  • Qiaohua He

  • Yan Feng

  • Linlin Liang

  • April 30, 2026

  • 0 min

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Tai Chi Plus Diet Improves Lifestyle and Health in PCOS Female College Students

Overview

A 6-month randomized controlled trial in female college students with PCOS demonstrated that combining Tai Chi with dietary adjustments significantly improved health-promoting lifestyle behaviors, reduced BMI, shortened menstrual cycle length, and lowered serum testosterone compared to diet alone. The intervention showed large behavioral effect sizes and modest metabolic and reproductive benefits.

Background

Polycystic ovary syndrome (PCOS) affects 5–20% of reproductive-age women and is characterized by menstrual irregularities, hyperandrogenism, and metabolic disturbances. Insulin resistance and hormonal imbalances contribute to its complex pathophysiology, increasing risks for metabolic syndrome and psychological comorbidities. Lifestyle modification, including diet and exercise, is first-line management, but adherence to conventional exercise is often poor among adolescents. Tai Chi, a traditional low-impact mind-body exercise, may offer a sustainable, accessible physical activity option with potential metabolic and psychosocial benefits.

Data Highlights

OutcomeIntervention (Diet + Tai Chi)Control (Diet Only)P-valueEffect Size (Cohen's d)
Health-Promoting Lifestyle Scale (Total Score Improvement)15.49 points (95% CI: 13.00–17.98)Reference<0.0012.62
Post-intervention BMI (kg/m²)21.35 ± 1.7622.51 ± 2.080.005Not reported
Menstrual Cycle Length (days)38.49 ± 6.3750.19 ± 12.04<0.001Not reported
Serum Testosterone Reduction (%)16.7%6.4%0.033Not reported

Key Findings

  • The combined Tai Chi and dietary intervention significantly improved overall health-promoting lifestyle behaviors, with the largest effect in the exercise dimension (Cohen's d = 2.69).
  • Participants in the intervention group had a significantly lower BMI post-intervention compared to controls (21.35 vs 22.51 kg/m², P = 0.005).
  • Menstrual cycle length was significantly shorter in the intervention group (38.49 vs 50.19 days, P < 0.001), indicating improved menstrual regularity.
  • Serum testosterone levels decreased more in the intervention group (16.7% reduction) than controls (6.4% reduction), with a significant between-group difference (P = 0.033).
  • Significant time × group interactions were observed for all outcomes except dietary nutrition, supporting the intervention's effect over time.
  • Exploratory analyses suggested greater benefits in participants with severe menstrual irregularities (>60 days), though these findings require confirmation.

Clinical Implications

Tai Chi combined with dietary modification may be a feasible and effective adjunctive lifestyle intervention for young women with PCOS, improving behavioral, metabolic, and reproductive health parameters. Its low-impact, accessible nature could enhance exercise adherence in this population. However, clinicians should interpret the large behavioral effect sizes cautiously due to measurement overlap and the lack of an active exercise comparator.

Conclusion

This randomized controlled study provides preliminary evidence that Tai Chi plus dietary adjustment improves lifestyle behaviors and key metabolic and reproductive outcomes in female college students with PCOS. Further multi-center trials with active comparators and long-term follow-up are needed to confirm these findings.

References

  1. Zhengzhou RCT 2025 -- Impact of Tai Chi and Dietary Modifications on Lifestyle, Metabolic, and Reproductive Health in Female College Students with PCOS

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