Investigation of Risk Factors Linked to Bloodstream Infections from Candida parapsilosis in Children and Factors Influencing Fluconazole Resistance: A 15-Year Retrospective Cohort Study - Report - MDSpire

Investigation of Risk Factors Linked to Bloodstream Infections from Candida parapsilosis in Children and Factors Influencing Fluconazole Resistance: A 15-Year Retrospective Cohort Study

  • By

  • Zumrut Sahbudak Bal

  • Sema Yildirim Arslan

  • Gizem Guner Ozenen

  • Gülizar Turan

  • Kübra Cebeci

  • Ulgen Celtik

  • Gulhadiye Avcu

  • Nihal Karadas

  • Gulcihan Ozek

  • Miray Karakoyun

  • Dilek Yesim Metin

  • Suleyha Hilmioglu Polat

  • January 8, 2026

  • 0 min

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Clinical Report: Investigation of Risk Factors Linked to Bloodstream Infections from Candida parapsilosis in Children

Overview

{'time_frame': 'Specify the exact years covered in the study.'}

Background

{'morbidity_mortality': 'Add statistics on morbidity and mortality rates in pediatric candidemia.'}

Data Highlights

{'incidence_data': 'Include specific numerical data for candidemia incidence.'}

Key Findings

{'resistance_rates': 'Verify and align resistance rates with the latest data.'}

Clinical Implications

{'empirical_therapy': 'Suggest specific antifungal therapies based on resistance.'}

Conclusion

{'further_research': 'Emphasize the need for additional studies on fluconazole resistance.'}

References

  1. Open Forum Infectious Diseases, 2023 -- Analysis of Candidemia Trends Over 14 Years: A Comparative Study of Candida parapsilosis and Candida albicans
  2. Infection, 2022 -- Epidemiology and Species Distribution of Candida Bloodstream Infections in Pediatric and Adult Populations at Two University Hospitals in Egypt: Initial Detection of Candida kefyr
  3. Infection, 2025 -- Analysis of Candida spp. Bloodstream Infections in Oncology Patients: A Retrospective Comparison from a Tertiary Cancer Center in Germany
  4. Infection, 2020 -- Rising Resistance to Echinocandins in Candida albicans and Candida glabrata in Switzerland
  5. Global guideline for the diagnosis and management of candidiasis, 2023 -- an initiative of the ECMM in cooperation with ISHAM and ASM
  6. BMC Infectious Diseases, 2026 -- Global prevalence and trends of fluconazole resistance in non-albicans Candida species: a systematic review and meta-analysis
  7. PubMed, 2023 -- The Paediatric European Confederation of Medical Mycology (ECMM) Quality (Paed-EQUAL) Candida Score for the Management of Candidaemia in Children and Neonates
  8. Global guideline for the diagnosis and management of candidiasis
  9. Global prevalence and trends of fluconazole resistance in non-albicans Candida species: a systematic review and meta-analysis | BMC Infectious Diseases | Springer Nature Link
  10. The Paediatric European Confederation of Medical Mycology (ECMM) Quality (Paed-EQUAL) Candida Score for the Management of Candidaemia in Children and Neonates - PubMed

Original Source(s)

Investigation of Risk Factors Linked to Bloodstream Infections from Candida parapsilosis in Children and Factors Influencing Fluconazole Resistance: A 15-Year Retrospective Cohort Study

  • by Zumrut Sahbudak Bal, Sema Yildirim Arslan, Gizem Guner Ozenen, Gülizar Turan, Kübra Cebeci, Ulgen Celtik, Gulhadiye Avcu, Nihal Karadas, Gulcihan Ozek, Miray Karakoyun, Dilek Yesim Metin, Suleyha Hilmioglu Polat

  • January 8, 2026

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