The first Dutch experience with a nurse-led outpatient clinic for the prevention and treatment of LARS after colorectal surgery: promising results of a standardized treatment protocol - Report - MDSpire

The first Dutch experience with a nurse-led outpatient clinic for the prevention and treatment of LARS after colorectal surgery: promising results of a standardized treatment protocol

  • By

  • C. Smit

  • M. L. Janssen-Heijnen

  • F. van Osch

  • M. van Heinsbergen

  • J. L. M. Konsten

  • December 30, 2025

  • 0 min

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Nurse-Managed Outpatient Clinic Shows Promise in Managing LARS Post-Colorectal Surgery

Overview

A Dutch nurse-led outpatient clinic implementing a standardized treatment protocol for Low Anterior Resection Syndrome (LARS) demonstrated encouraging improvements in bowel function and quality of life among colorectal surgery patients. Systematic screening and multidisciplinary management facilitated early identification and tailored interventions, resulting in significant symptom reduction.

Background

Low Anterior Resection Syndrome (LARS) is a common and debilitating condition affecting up to 90% of patients after rectal cancer surgery, characterized by persistent bowel dysfunction. Its heterogeneous presentation complicates management, often requiring multifaceted and individualized treatment approaches. Prior studies have focused on single modalities, but comprehensive nurse-led protocols integrating education, pharmacological treatment, dietary advice, physiotherapy, and psychological support may improve outcomes. The Dutch clinic established in 2021 is the first of its kind in the Netherlands, offering standardized screening and multidisciplinary care for all colorectal surgery patients at risk of LARS.

Data Highlights

Outcome MeasurePre-TreatmentPost-TreatmentSignificance
Median LARS Score3118p = 0.02
Wexner ScoreNot specifiedImprovedNot specified
Quality of Life SubdomainsBaselineImprovedNot specified

Key Findings

  • The nurse-led outpatient clinic systematically screened all colorectal surgery patients pre- and postoperatively using validated tools including the LARS and Wexner scores.
  • Implementation of a standardized treatment protocol led to a significant reduction in median LARS scores from 31 to 18 (p = 0.02).
  • Multidisciplinary care involved colorectal care nurses, surgeons, dietitians, psychologists, and pelvic floor physiotherapists, ensuring comprehensive management.
  • Early education and tailored pharmacological, dietary, and physiotherapeutic interventions were integral to symptom improvement.
  • Persistent major LARS cases were escalated to advanced treatments such as transanal irrigation, sacral neuromodulation, or colostomy as appropriate.
  • The clinic also accepted referrals for patients with LARS symptoms following various colorectal resections beyond rectal cancer surgery.

Clinical Implications

This nurse-managed, multidisciplinary approach enables early identification and individualized treatment of LARS, improving patient outcomes and quality of life. Incorporating standardized screening and protocol-driven management into colorectal surgical care pathways may optimize symptom control and reduce the burden of LARS. Clinicians should consider establishing similar nurse-led clinics to provide coordinated, evidence-based care for this complex syndrome.

Conclusion

The Dutch nurse-led LARS outpatient clinic demonstrates that a structured, multidisciplinary protocol can effectively reduce bowel dysfunction symptoms and enhance quality of life in colorectal surgery patients. These promising results support broader implementation of such models in clinical practice.

References

  1. Dalsgaard et al. 2021 -- Nurse-led standardized intervention for bowel dysfunction post rectal cancer surgery
  2. VieCuri Medical Centre Study 2021-2024 -- Nurse-led LARS outpatient clinic protocol and outcomes

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