Ultrasound-guided, nursing-led, phase-based swallowing rehabilitation in elderly patients with MIBG-positive medullary thyroid carcinoma following 131I-MIBG therapy - Report - MDSpire

Ultrasound-guided, nursing-led, phase-based swallowing rehabilitation in elderly patients with MIBG-positive medullary thyroid carcinoma following 131I-MIBG therapy

  • By

  • Chunyan Hu

  • June 22, 2026

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Nursing-led, ultrasound-assisted swallowing rehabilitation in older adults

Overview

This study evaluates the effectiveness of ultrasound-guided, nursing-led swallowing rehabilitation in elderly patients with MIBG-positive medullary thyroid carcinoma following 131I-MIBG therapy.

Background

Medullary thyroid carcinoma (MTC) is a rare neuroendocrine malignancy that often leads to dysphagia and malnutrition, particularly in elderly patients. Traditional rehabilitation approaches have shown limited effectiveness, highlighting the need for innovative, technology-assisted strategies.

Data Highlights

Outcome MeasureUltrasound GroupConventional GroupP-value
FOIS Improvement+2.1 ± 0.5+1.2 ± 0.6< 0.001
MDADI Improvement+32%+18%< 0.001
EAT-10 Change−6.8 ± 2.1−3.4 ± 1.9< 0.001
Aspiration Events9%15%N/A
Pneumonia-related Readmissions5%15%N/A

Key Findings

  • Ultrasound-guided rehabilitation resulted in greater FOIS improvement compared to conventional methods.
  • MDADI scores improved significantly more in the ultrasound group.
  • EAT-10 scores showed a greater reduction in the ultrasound group.
  • Suprahyoid muscle thickness increased by 24% in the ultrasound group.
  • Aspiration events decreased from 15% to 9% in the ultrasound group.
  • No adverse events related to rehabilitation were reported.

Clinical Implications

The findings indicate the potential for integrating ultrasound into swallowing rehabilitation for elderly patients with dysphagia following 131I-MIBG therapy.

Conclusion

Ultrasound-guided, nursing-led swallowing rehabilitation appears to improve swallowing function and quality of life in elderly patients with MIBG-positive MTC.

Related Resources & Content

  1. Frontiers in Neurology, 2026 -- Efficacy observation of electromyography-guided targeted injection of swallowing muscles for treating dysphagia resulting from medullary paralysis
  2. Frontiers in Neurology, 2026 -- Left Vagus Nerve Magnetic Stimulation Facilitates Nasogastric Tube Removal in Post-Stroke Patients with Dysphagia: A Prospective Observational Cohort Study
  3. Journal of Neuro-Oncology, 2024 -- Postoperative Rehabilitation During Chemoradiotherapy Enhances Functional Outcomes and Survival in Glioblastoma Patients, Regardless of Age
  4. NCCN Guidelines® Insights: Thyroid Carcinoma, Version 1.2025 - PubMed
  5. Surgical Endoscopy — Utilization of Intraoperative Neuromonitoring Decreases Risk of Vocal Cord Damage During Open Surgery for Thyroid Cancer: Findings from a Randomized Controlled Study
  6. NCCN Guidelines® Insights: Thyroid Carcinoma, Version 1.2025 - PubMed
  7. Scintigraphy and treatment of medullary carcinoma of the thyroid with iodine-131 metaiodobenzylguanidine - PubMed
  8. Prevalence and Risk Factors for Dysphagia in Older Adults Following Thyroid and Parathyroid Surgery - PMC

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