The characteristics and outcomes of vascular abnormalities involving limbs in children: a retrospective analysis of 35 cases - Report - MDSpire

The characteristics and outcomes of vascular abnormalities involving limbs in children: a retrospective analysis of 35 cases

  • By

  • Haiyin Zhou

  • Xiangyu Yang

  • Jialong Nie

  • Zixiao Wang

  • Ting Lei

  • Kun Liu

  • Guanghui Zhu

  • July 14, 2026

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Clinical Report: Analysis of Limb Vascular Abnormalities in Pediatric Patients

Overview

This study retrospectively analyzed 35 pediatric cases of limb vascular abnormalities, focusing on clinical characteristics, diagnostic criteria, and surgical outcomes.

Background

Vascular malformations in children are relatively common, with an incidence of 1.5% in the population. These conditions can lead to significant physical and psychological impacts due to their potential to cause pain, dysfunction, and misdiagnosis.

Data Highlights

CharacteristicValue
Number of cases35
Male18 (51.4%)
Female17 (48.6%)
Average age at surgery7.4 ± 3.2 years
Lesion locations (upper/lower limbs)16/19
Main clinical manifestationsLocalized masses (91.4%), pain (54.3%)
Surgical complication rate11.4%
Recurrence rate5.7%

Key Findings

  • Localized masses were the main clinical manifestation in 91.4% of cases.
  • The average size of masses was 3.8 ± 2.3 cm.
  • Venous malformations were the most common type, accounting for 40.0% of cases.
  • The surgical complication rate was 11.4%, with a recurrence rate of 5.7%.
  • No significant differences in complication or recurrence rates were observed among different pathological types.

Clinical Implications

Clinicians should be aware of the common clinical presentations to reduce misdiagnosis and improve management outcomes.

Conclusion

The study provides insights into the clinical characteristics and surgical outcomes of limb vascular abnormalities in children.

Related Resources & Content

  1. Frontiers in Pediatrics, 2026 -- Efficacy of interventions in peripheral arterial and venous malformations of the limbs in children: protocol for a systematic review
  2. Frontiers in Pediatrics, 2026 -- Case Report: Clinical management of genital, perineal, and perianal venous malformation in a five-year-old boy: therapeutic decision-making and review of current literature
  3. Frontiers in Pediatrics, 2026 -- Venous malformation with localized intravascular coagulopathy in children treated with sclerotherapy and LWMH
  4. Pediatric Cardiology, 2010 -- Two Instances of Cardiac Arteriovenous Malformation Associated with a Localized Angioproliferative Condition
  5. Classification | International Society for the Study of Vascular Anomalies
  6. Management and Outcomes of Pediatric Lymphatic Malformations: A Systematic Review From the APSA Outcomes and Evidence-Based Practice Committee
  7. Diagnosis and management of superficial arteriovenous malformations: French healthcare network’s recommendations | Orphanet Journal of Rare Diseases
  8. ISSVA Classification & Glossary for Vascular Anomalies
  9. APSA Outcomes and Evidence‑Based Practice Committee systematic review
  10. Diagnosis and management of superficial arteriovenous malformations: French healthcare network’s recommendations | Orphanet Journal of Rare Diseases | Springer Nature Link

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