Clinical Report: Outcomes After Two Years of Trabeculo-canalectomy in Patients with Glaucoma Related to Iridocorneal Endothelial Syndrome

Overview

This study evaluates the two-year outcomes of trabeculo-canalectomy in patients with glaucoma secondary to iridocorneal endothelial syndrome (GS-ICE). The procedure resulted in significant reductions in intraocular pressure (IOP) and anti-glaucoma medication use.

Background

Iridocorneal endothelial (ICE) syndrome is a rare condition that can lead to secondary glaucoma, affecting a significant proportion of patients. Traditional surgical options like trabeculectomy often yield poor outcomes due to complications associated with the disease.

Data Highlights

Key Findings

• The complete success rate of trabeculo-canalectomy at 2 years was 80.8%.
• Conditional success rate was 11.5%.
• Postoperative mean IOP significantly decreased from 31.10 mmHg preoperatively to 16.89 mmHg at 2 years (p < 0.001).
• The number of anti-glaucoma medications was significantly reduced to 0 at all follow-up visits (p < 0.001).
• Hyphema was the most common early-stage complication, occurring in 7.7% of patients.
• Two cases of corneal edema were noted, which did not involve elevated IOP.

Clinical Implications

Trabeculo-canalectomy appears to be an effective surgical option for managing IOP in patients with GS-ICE, leading to significant reductions in both IOP and medication requirements. The low complication rate further supports its use in this patient population.

Conclusion

The findings suggest that trabeculo-canalectomy offers favorable outcomes for patients with GS-ICE, highlighting its potential as a viable surgical intervention for this challenging condition.

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