Patient outcomes and healthcare utilisation following implementation of an advanced therapy care pathway for inflammatory bowel disease: a multicentre, prospective quasi-experimental preimplementation/postimplementation study in the Netherlands - Report - MDSpire
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Evaluating Patient Outcomes and Healthcare Utilization After the Introduction of an Advanced Therapy Care Pathway for Inflammatory Bowel Disease: A Multicenter, Prospective Quasi-Experimental Study in the Netherlands

  • By

  • Elyke H Visser

  • Martijn A Oude Voshaar

  • Reinier C A Van Linschoten

  • Jildou Hoekstra

  • Kristin Robbers

  • Vincent de Jonge

  • Edith Koehler

  • K Evelyne Verweij

  • Sanne van der Wiel

  • Daniëlle van der Horst

  • C Janneke van der Woude

  • Desiree van Noord

  • Rachel L West

  • on behalf of the Southwest Netherlands IBD Study Group

  • October 1, 2026

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Clinical Report: Evaluating Patient Outcomes and Healthcare Utilization After ACP for IBD

Overview

This study assesses the impact of an advanced therapy care pathway (ACP) on patient outcomes and healthcare utilization in inflammatory bowel disease (IBD) patients in the Netherlands. Results indicate a significant reduction in hospital admissions post-implementation.

Background

Inflammatory bowel diseases (IBDs) impose a significant economic burden on healthcare systems due to high healthcare utilization and treatment costs. The implementation of structured care pathways aims to standardize treatment and reduce variation in clinical practice.

Data Highlights

MetricPre-ImplementationPost-ImplementationDiD Estimate (95% CI)
Emergency Room VisitsData not providedDecreased-0.05 (-0.10 to 0.01)
Hospital AdmissionsData not providedDecreased-0.06 (-0.11 to -0.03)
Disease ControlHighUnchanged0.12 (-0.74 to 1.01)

Key Findings

  • The study included 1173 patients, with a median age of 45 years and 55% female.
  • Crohn’s disease was the most prevalent condition, accounting for 64% of cases.
  • Six months post-implementation, emergency room visits and hospital admissions significantly decreased.
  • The ACP did not compromise disease control.

Clinical Implications

The implementation of an ACP for IBD may assist healthcare providers in delivering standardized care.

Conclusion

The study demonstrates that an ACP can achieve outcomes comparable to standard practice while reducing hospital admissions.

Related Resources & Content

  1. Journal of Crohn's and Colitis, 2023 -- Evaluating Patient Outcomes and Healthcare Utilization After ACP for IBD
  2. ECCO Guidelines on Therapeutics in Ulcerative Colitis: Medical Treatment, Journal of Crohn's and Colitis, 2026
  3. ASCO Publications — Clinical treatment pathways utilization in an outpatient academic cancer center.
  4. Prevalence of Clinical Remission and Insufficient Response to Advanced Treatments in Ulcerative Colitis Patients in Germany
  5. ASCO Publications — Results From a Health Insurer's Clinical Pathway Program in Breast Cancer
  6. Clinical treatment pathways utilization in an outpatient academic cancer center.
  7. Prevalence of Clinical Remission and Insufficient Response to Advanced Treatments in Ulcerative Colitis Patients in Germany.
  8. ECCO Guidelines on Therapeutics in Ulcerative Colitis: Medical Treatment | Journal of Crohn's and Colitis | Oxford Academic
  9. Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis | New England Journal of Medicine
  10. Quality of Care Standards in Inflammatory Bowel Diseases: a European Crohn’s and Colitis Organisation [ECCO] Position Paper | Journal of Crohn's and Colitis | Oxford Academic

Original Source(s)

Patient outcomes and healthcare utilisation following implementation of an advanced therapy care pathway for inflammatory bowel disease: a multicentre, prospective quasi-experimental preimplementation/postimplementation study in the Netherlands

  • by Elyke H Visser, Martijn A Oude Voshaar, Reinier C A Van Linschoten, Jildou Hoekstra, Kristin Robbers, Vincent de Jonge, Edith Koehler, K Evelyne Verweij, Sanne van der Wiel, Daniëlle van der Horst, C Janneke van der Woude, Desiree van Noord, Rachel L West, on behalf of the Southwest Netherlands IBD Study Group

  • October 1, 2026

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