Physical activity intensity and cardiovascular disease in Southwest China: a study on data from the China Multi-Ethnic Cohort study - Report - MDSpire

Physical activity intensity and cardiovascular disease in Southwest China: a study on data from the China Multi-Ethnic Cohort study

  • By

  • Yanjiao Wang

  • Likun He

  • Yanjiao Luo

  • Ying Qian

  • Jizhuo Yang

  • Xuehui Zhang

  • Jianzhong Yin

  • June 30, 2026

  • 0 min

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Association Between Levels of Physical Activity and Cardiovascular Disease in Yunnan Province, China

Overview

This study investigates the relationship between physical activity intensity and cardiovascular disease (CVD) in Yunnan Province, finding that vigorous physical activity (VPA) is associated with lower odds of prevalent CVD compared to low physical activity (LPA).

Background

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality globally, with increasing prevalence in China, especially in less-developed regions. Physical activity is a modifiable risk factor for CVD, yet the independent effects of varying intensities of physical activity have not been thoroughly examined in high-altitude populations. Understanding these relationships is crucial for developing targeted interventions in regions like Yunnan Province, where unique environmental factors may influence cardiovascular health.

Data Highlights

Physical Activity IntensityOdds Ratio (95% CI)P-trend
VPA vs LPA (Crude Model)0.10 (0.04, 0.26)< 0.001
VPA vs LPA (Adjusted for Age and Sex)0.30 (0.11, 0.85)0.018
VPA vs LPA (Fully Adjusted)0.27 (0.09, 0.80)0.025

Key Findings

  • Among 10,447 participants, 267 (2.56%) had cardiovascular disease (CVD).
  • Vigorous physical activity (VPA) was associated with significantly lower odds of CVD compared to low physical activity (LPA).
  • After adjusting for various confounders, the odds of CVD remained lower for VPA compared to LPA.
  • A significant interaction was found between waist circumference and physical activity intensity regarding CVD odds.
  • The study emphasizes the need for intensity-specific physical activity investigations in high-altitude populations.

Clinical Implications

The findings suggest that promoting vigorous physical activity may be an effective strategy for reducing cardiovascular disease risk in populations living at high altitudes. Clinicians should consider the intensity of physical activity when advising patients on lifestyle modifications for cardiovascular health.

Conclusion

Vigorous physical activity is associated with lower odds of prevalent cardiovascular disease in the Yunnan Province population.

Related Resources & Content

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  8. https://www.healthquality.va.gov/HEALTHQUALITY/guidelines/CD/lipids/Lipids-CPG_2025-Guideline_final_20260106.pdf
  9. Joint association of sedentary behaviour and physical activity with cardiovascular disease: a systematic review and meta-analysis | European Journal of Preventive Cardiology | Oxford Academic
  10. Association between physical activity and incident atherosclerotic cardiovascular disease is modified by predicted cardiovascular risk: The China-PAR project - ScienceDirect

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