Clinical Report: Advanced Biventricular Failure in a Case of Double-Chambered Left Ventricle

Background

Double-chambered left ventricle (DCLV) is an uncommon congenital anomaly characterized by an aberrant septum that divides the left ventricular cavity. While typically diagnosed in childhood, adult cases are rare and often present with significant complications such as heart failure and valvular dysfunction.

Data Highlights

No numerical data or trial data available in the source material.

Key Findings

• A 50-year-old male with DCLV presented with exertional chest tightness and dyspnea.
• Echocardiography revealed a muscular septum with a peak gradient of 7 mmHg and severe mitral regurgitation.
• The patient had a left ventricular ejection fraction of 29.4% and a significant burden of premature ventricular complexes.
• Despite one month of optimized guideline-directed therapy, there was no improvement in symptoms or functional capacity.
• The heart team recommended evaluation for orthotopic heart transplantation due to complex surgical anatomy and refractory heart failure.

Clinical Implications

This case presents a patient with DCLV and advanced heart failure, highlighting the complexity of management in such cases.

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